New drug duo shows promise for rare cancers that Won't stop growing
NCT ID NCT05142241
First seen Nov 01, 2025 · Last updated Jun 15, 2026 · Updated 30 times
Summary
This study tests whether combining two drugs, talazoparib and temozolomide, can shrink or stop the growth of rare cancers that have spread. The drugs work by damaging cancer cell DNA and blocking its repair. The trial includes 14 adults with advanced rare solid tumors, like pheochromocytoma or paraganglioma, who have run out of standard options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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National Cancer Institute Developmental Therapeutics Clinic
Bethesda, Maryland, 20892, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
Conditions
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