New rapid test could slash antibiotic misuse in hospital pneumonia

NCT ID NCT04153682

Completed Diagnosis Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This study tested whether a fast diagnostic test (FilmArray) plus expert antibiotic advice improves care for patients who develop pneumonia in the hospital. 116 adults with hospital-acquired pneumonia were randomly assigned to get either standard care with expert advice or the same plus the rapid test. The goal was to see if the rapid test helps doctors use fewer broad-spectrum antibiotics and improve patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rapid diagnostic test (FilmArray Pneumonia Panel) and antimicrobial stewardship team intervention
What this could lead to: If successful, this approach could help doctors choose the right antibiotics faster, reducing side effects and antibiotic resistance.
What could go wrong: This is a small, completed trial with 116 patients, so results may not apply to all hospitals or patients. The test may not always be accurate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Healthcare-Associated Pneumonia nosocomial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HOSPITAL-ACQUIRED PNEUMONIA

Contacts and locations

Locations

CHRU Nancy

Nancy, 54511, France
Groupe Hospitalier Paris Saint Joseph

Paris, 75014, France
Hôpitaux Universitaires Henri Mondor

Créteil, 94010, France
Hôpitaux Universitaires Paris Centre (Cochin) - service Médecine Intensive - Réanimation

Paris, 75006, France
Hôpitaux Universitaires Paris Centre-Site Cochin

Paris, 75014, France
Hôpitaux Universitaires Paris Nord Val de Seine - EPRI (Bichat)

Paris, France
Hôpitaux Universitaires Paris Nord Val de Seine - MIR (Bichat)

Paris, France
Hôpitaux Universitaires Paris Nord Val de Seine-Site Bichat (SMIT)

Paris, 75018, France

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