Heart attack patients may benefit from Clot-Busting drug before delayed procedure
NCT ID NCT07641231
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at 240 adults having a major heart attack (STEMI) when the standard emergency procedure to open the blocked artery is expected to be delayed by over an hour. Half will get a clot-busting drug (tenecteplase) right away, followed by the procedure within 2-24 hours. The other half will just have the standard procedure. The goal is to see if the early drug reduces the risk of death, stroke, or another heart attack within a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- tenecteplase
- What this could lead to
- If successful, this could show that giving a clot-busting drug early, even when a hospital can do a standard procedure, improves survival and reduces complications after a heart attack.
- What could go wrong
- This is a Phase 4 study with only 240 participants, so results may not apply to everyone. The clot-busting drug also increases bleeding risk, which could offset any benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Moscow, Select A State, 121552, Russia
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