New combo therapy aims to extend remission in aggressive lung cancer
NCT ID NCT05718323
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests whether adding the drug niraparib to standard maintenance therapy can help people with a specific type of advanced small cell lung cancer (SLFN11-positive) stay cancer-free longer. About 44 participants will receive niraparib pills plus an anti-PD-L1 antibody after initial chemo-immunotherapy. The main goal is to see how many patients have no cancer growth after 3 months.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Bürgerspital Solothurn
RECRUITINGSolothurn, Switzerland
Contact Email: •••••@•••••
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CHU - Angers
RECRUITINGAngers, France
Contact Email: •••••@•••••
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Caen - CHU
RECRUITINGCaen, France
Contact Email: •••••@•••••
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Centre Hospitalier d'Avignon
RECRUITINGAvignon, France
Contact Email: •••••@•••••
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Centre Hospitalier du Valais Romand
RECRUITINGSion, Switzerland
Contact Email: •••••@•••••
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Complejo Hospitalario Universitario a Coruña
NOT_YET_RECRUITINGA Coruña, Spain
Contact
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Complejo Hospitalario de Jaén
RECRUITINGJaén, Spain
Contact
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Hospital Universitario Puerta de Hierro
RECRUITINGMadrid, Spain
Contact
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Inselspital Bern
RECRUITINGBern, Switzerland
Contact Email: •••••@•••••
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Instituto Europeo di Oncologia (IEO)
NOT_YET_RECRUITINGMilan, Italy
Contact Email: •••••@•••••
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Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST)
RECRUITINGMeldola, Italy
Contact Email: •••••@•••••
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Kantonsspital Baden
RECRUITINGBaden, Switzerland
Contact Email: •••••@•••••
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Kantonsspital St. Gallen
RECRUITINGSankt Gallen, Switzerland
Contact Email: •••••@•••••
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Kantonsspital Winterthur
RECRUITINGWinterthur, Switzerland
Contact Email: •••••@•••••
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LMU Klinikum / Thoracic Oncology center Münich
RECRUITINGMünchen, Germany
Contact
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Lyon - Centre Léon Bérard
NOT_YET_RECRUITINGLyon, France
Contact Email: •••••@•••••
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Santa Maria della Misericordia Hospital
RECRUITINGPerugia, Italy
Contact Email: •••••@•••••
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University Hospital Basel
RECRUITINGBasel, Switzerland
Contact Email: •••••@•••••