Radioactive drug combo shows promise for advanced prostate cancer
NCT ID NCT03361735
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial is testing a combination of radium-223 (a radioactive drug that targets bone tumors), hormone therapy, and precise radiation for men with prostate cancer that has spread to a few other places in the body. The goal is to see if this triple approach can delay cancer progression better than standard treatments. The study enrolled 25 participants and is no longer recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radium Ra 223 dichloride (a radioactive drug that targets bone tumors)
- What this could lead to
- If successful, this combination could offer a new way to delay cancer progression in men with prostate cancer that has spread to a few spots in the body.
- What could go wrong
- This is a small, early-phase trial with only 25 participants, so results may not apply to everyone. The treatment involves radiation and hormone therapy, which can cause side effects like fatigue, bone pain, and hormonal changes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
City of Hope Medical Center
Duarte, California, 91010, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can surgery boost control of spread prostate cancer?
- Can a better scan sharpen radiation for prostate cancer?
- Hormone therapy showdown: can an oral pill beat the shot for prostate cancer patients?
- Can tracking tumor movement during radiation make treatment more precise?
- Can a single small incision preserve sexual function after prostate cancer surgery?
- Can a shorter course of radiation tame prostate cancer with fewer side effects?