New combo therapy aims to boost immune attack on tough breast cancer
NCT ID NCT06735131
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing different ways to combine radiotherapy with the immunotherapy drug toripalimab and chemotherapy for people with advanced triple-negative breast cancer (TNBC). The goal is to find the best schedule that helps control the cancer longer. About 60 participants will receive one of several radiotherapy patterns alongside standard treatment, and researchers will track how many are still progression-free after 6 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- toripalimab (immunotherapy) plus radiotherapy and chemotherapy
- What this could lead to
- If successful, this could establish a more effective combination treatment for advanced triple-negative breast cancer, potentially improving how long patients live without their cancer worsening.
- What could go wrong
- This is a small, early-phase trial with only 60 participants, so results may not apply to all patients. The added radiotherapy also carries risks like fatigue, skin reactions, or inflammation of nearby organs.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510060, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can your own immune cells fight advanced cancer?
- Can a biomarker spare breast cancer patients from harsh chemo?