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Can a quick office procedure unblock stuffy noses without surgery?

NCT ID NCT07772505

Disease control Sponsor: Goh Liang Chye Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time

Summary

This trial compares two procedures done in the clinic to treat nasal blockage caused by enlarged turbinates—the small structures inside the nose. One uses radiofrequency energy to shrink the tissue, while the other uses an instrument to push the turbinates aside. Adults with moderate-to-severe nasal obstruction who haven't improved with medication will be randomly assigned to one of the two procedures. The study tracks changes in nasal obstruction symptoms and turbinate size over six months to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Radiofrequency ablation or lateralization of the inferior turbinates, both office-based procedures to reduce turbinate size and improve nasal airflow.
What this could lead to
If successful, this could identify which clinic-based procedure is more effective and safer for relieving nasal obstruction, offering a quicker alternative to surgery.
What could go wrong
This is a small, early-stage comparative study. Both procedures carry risks like pain, bleeding, crusting, and symptom recurrence, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

54 people

The number who actually took part.

Started

Nov 2020

Finished

Jun 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Bilateral inferior turbinate hypertrophy, Grade 3 or 4 (25% Inferior Turbinate Classification System) Age more than 18 years NOSE score more than 30 On conventional pharmacological therapy for more than 3 months Exclusion Criteria: Severe deviated nasal septum or caudal dislocation Nasal polyposis Nasal valve disorder Allergy or contraindication to Marcaine (bupivacaine) with adrenaline, or to Co-Phenylcaine

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Conditions

The condition(s) this trial relates to.

Nasal Obstruction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inferior turbinates hypertrophy Nasal obstruction

Contacts and locations

Locations

  • Tengku Ampuan Rahimah Hospital

    Klang, Selangor, 41200, Malaysia

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