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Massive study tracks radiation therapy results to improve cancer care

NCT ID NCT01255748

Knowledge-focused Sponsor: Proton Collaborative Group Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study is collecting information from up to 40,000 cancer patients who are receiving radiation therapy. Researchers will track their outcomes to better understand what works and how to reduce side effects. The goal is to improve patient care by learning from real-world treatment results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50,000 people

The number the study aims to enrol. It can still change while the study runs.

Start date

Jun 2009

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Radiation Oncology patients

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Planned treatment with radiation therapy * Ability to understand and sign IRB approved consent

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    29 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ackerman Cancer Center

    RECRUITING

    Jacksonville, Florida, 32223, United States

  • Atrium Health Levine Cancer Proton & Advanced Radiation Center

    RECRUITING

    Charlotte, North Carolina, 28204, United States

  • California Protons Cancer Therapy Center

    RECRUITING

    San Diego, California, 92121, United States

  • Dwoskin Proton Therapy Center

    RECRUITING

    Miami, Florida, 33125, United States

  • Emory Proton Therapy Center

    RECRUITING

    Atlanta, Georgia, 30308, United States

  • Hampton University Proton Therapy Institute

    RECRUITING

    Hampton, Virginia, 23666, United States

  • Inova Schar Cancer Institute

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • Kansas City Proton Institute

    RECRUITING

    Overland Park, Kansas, 66207, United States

  • Maryland Proton Treatment Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

  • Mayo Clinic

    RECRUITING

    Scottsdale, Arizona, 85259-5499, United States

  • McLaren Proton Therapy Center

    RECRUITING

    Flint, Michigan, 48532, United States

  • Mercy David C. Pratt Cancer Center

    RECRUITING

    St Louis, Missouri, 63141, United States

  • Miami Cancer Institute

    RECRUITING

    Miami, Florida, 33176, United States

  • New York Proton Center

    RECRUITING

    New York, New York, 10035, United States

  • Northwestern Medicine Chicago Proton Center

    RECRUITING

    Warrenville, Illinois, 60555, United States

  • OSF HealthCare Cancer Institute

    RECRUITING

    Peoria, Illinois, 61603, United States

  • Oklahoma Proton Center

    RECRUITING

    Oklahoma City, Oklahoma, 73142, United States

  • Orlando Health Cancer Institute

    RECRUITING

    Orlando, Florida, 32806, United States

  • ProCure Proton Therapy Center

    RECRUITING

    Somerset, New Jersey, 08873, United States

  • Proton Center of Arkansas

    RECRUITING

    Little Rock, Arkansas, 72205, United States

  • South Florida Proton Therapy Institute

    RECRUITING

    Delray Beach, Florida, 33484, United States

  • Southwest Florida Proton Center

    RECRUITING

    Fort Myers, Florida, 33967, United States

  • Tennessee Oncology Proton Center

    RECRUITING

    Franklin, Tennessee, 37067, United States

  • Texas Center for Proton Therapy

    RECRUITING

    Irving, Texas, 75063, United States

  • Thompson Proton Center

    RECRUITING

    Knoxville, Tennessee, 37909, United States

  • University of Cincinnati Medical Center

    RECRUITING

    Cincinnati, Ohio, 45044, United States

  • University of Kansas Proton Therapy Center

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195-6043, United States

  • Willis-Knighton Cancer and Proton Therapy Center

    RECRUITING

    Shreveport, Louisiana, 71103, United States

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