New hope for recurrent throat cancer: Radiation-Immunotherapy combo shows promise

NCT ID NCT07277764

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests a new approach for recurrent nasopharyngeal carcinoma (a type of throat cancer) that has come back after initial treatment and cannot be removed by surgery. The treatment combines a special radiation schedule (low and high doses) with an immunotherapy drug (anti-PD-1) to boost the immune system's attack on cancer cells. The study will enroll 23 participants and measure how well the cancer responds after 3 months, as well as long-term survival and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anti-PD-1 monoclonal antibody (nivolumab or similar)
What this could lead to
If successful, this could offer a new treatment option for patients with recurrent nasopharyngeal carcinoma who cannot have surgery.
What could go wrong
This is a small, early-phase trial with only 23 participants, so results may not apply to everyone. The combination of radiation and immunotherapy may cause side effects like immune-related inflammation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jiangxi Cancer Hospital

    RECRUITING

    Nanchang, Jiangxi, 330029, China

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