New hope for recurrent throat cancer: Radiation-Immunotherapy combo shows promise
NCT ID NCT07277764
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests a new approach for recurrent nasopharyngeal carcinoma (a type of throat cancer) that has come back after initial treatment and cannot be removed by surgery. The treatment combines a special radiation schedule (low and high doses) with an immunotherapy drug (anti-PD-1) to boost the immune system's attack on cancer cells. The study will enroll 23 participants and measure how well the cancer responds after 3 months, as well as long-term survival and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Anti-PD-1 monoclonal antibody (nivolumab or similar)
- What this could lead to
- If successful, this could offer a new treatment option for patients with recurrent nasopharyngeal carcinoma who cannot have surgery.
- What could go wrong
- This is a small, early-phase trial with only 23 participants, so results may not apply to everyone. The combination of radiation and immunotherapy may cause side effects like immune-related inflammation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Jiangxi Cancer Hospital
RECRUITINGNanchang, Jiangxi, 330029, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can an immunotherapy boost standard treatment for a Head-and-Neck cancer?
- Can a Two-Pronged radiation strategy boost immunotherapy against advanced nasopharyngeal cancer?
- Can tumor genetics predict survival in nasopharyngeal cancer?
- Dual-Action antibody may boost chemoradiotherapy against High-Risk nasopharyngeal cancer