New hope for recurrent throat cancer: Radiation-Immunotherapy combo shows promise

NCT ID NCT07277764

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests a new approach for recurrent nasopharyngeal carcinoma (a type of throat cancer) that has come back after initial treatment and cannot be removed by surgery. The treatment combines a special radiation schedule (low and high doses) with an immunotherapy drug (anti-PD-1) to boost the immune system's attack on cancer cells. The study will enroll 23 participants and measure how well the cancer responds after 3 months, as well as long-term survival and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Anti-PD-1 monoclonal antibody (nivolumab or similar)

What this could lead to

If successful, this could offer a new treatment option for patients with recurrent nasopharyngeal carcinoma who cannot have surgery.

What could go wrong

This is a small, early-phase trial with only 23 participants, so results may not apply to everyone. The combination of radiation and immunotherapy may cause side effects like immune-related inflammation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

nasopharyngeal carcinoma nasopharyngeal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jiangxi Cancer Hospital

    RECRUITING

    Nanchang, Jiangxi, 330029, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••