Can a natural antioxidant tame inflammation in rare immune disorder?
NCT ID NCT07433621
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study is testing whether quercetin, a natural antioxidant found in foods, is safe and can reduce inflammation in male patients with XIAP deficiency, a rare genetic immune disorder. Twelve participants will take oral quercetin daily. The main goals are to check for side effects and see if the drug is tolerable, with a secondary look at how the body processes it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- quercetin
- What this could lead to
- If it works, this could point toward a way to manage inflammation in XIAP deficiency, potentially improving daily life for patients.
- What could go wrong
- This is a very early, small pilot study with only 12 participants. It primarily tests safety, not effectiveness, and quercetin may not reduce inflammation as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cincinnati Children's Hospital Medical Center
RECRUITINGCincinnati, Ohio, 45229, United States