Knee pain drug trial halted early – what happened?

NCT ID NCT05462990

First seen Feb 02, 2026 · Last updated May 25, 2026 · Updated 13 times

Summary

This study tested an experimental drug called QUC398 in 101 people with painful knee osteoarthritis. The goal was to see if it could reduce pain and protect knee cartilage. The trial was stopped early, so results are limited.

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Contacts and locations

Locations

  • Boston Univ School of Medicine

    Boston, Massachusetts, 02118, United States

  • Clinical Research of West Florida Inc

    Tampa, Florida, 33603, United States

  • Novartis Investigative Site

    Southport, Queensland, 4222, Australia

  • Novartis Investigative Site

    Christchurch, 8011, Australia

  • Novartis Investigative Site

    St Leonards, 2065, Australia

  • Novartis Investigative Site

    Herlev, 2730, Denmark

  • Novartis Investigative Site

    Vejle, 7100, Denmark

  • Novartis Investigative Site

    Nice, 06001, France

  • Novartis Investigative Site

    Orléans, 45100, France

  • Novartis Investigative Site

    Sabadell, Barcelona, 08208, Spain

  • Novartis Investigative Site

    Leganés, Madrid, 28915, Spain

  • Novartis Investigative Site

    A Coruña, 15006, Spain

  • Novartis Investigative Site

    Seville, 41010, Spain

  • West Clinical Research

    Morehead City, North Carolina, 28557, United States

Conditions

Explore the condition pages connected to this study.