New ALS drug trial seeks safer treatment, not a cure

NCT ID NCT05633459

First seen May 15, 2026 · Last updated May 15, 2026

Summary

This early-stage study tests the safety of a new drug called QRL-201 in 69 people with ALS, a nerve disease that weakens muscles. Participants receive either the drug or a placebo to check for side effects. The goal is to see if QRL-201 is safe enough for further testing, not to cure the disease.

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Contacts and locations

Locations

  • CHUM - Hopital Notre-Dame

    Montreal, Quebec, H2L 4M1, Canada

  • Charité Research Organisation

    Berlin, 10117, Germany

  • Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE)

    Bonn, North Rhine-Westphalia, 53127, Germany

  • Kings College Hospital NHS Foundation Trust

    London, SE5 9RS, United Kingdom

  • Montreal Neurological Institute-Hospital

    Montreal, Quebec, H3A 2B4, Canada

  • National Hospital for Neurology and Neurosurgery

    London, WC1N 3BG, United Kingdom

  • St James's Hospital

    Dublin, D08 A978, Ireland

  • Sunnybrook Health Science Centre

    Toronto, Ontario, M4N 3M5, Canada

  • The University of Sheffield, Royal Hallamshire Hospital

    Sheffield, United Kingdom, S10 2JF, United Kingdom

  • Universitair Medisch Centrum Utrecht

    Utrecht, Netherlands

  • Universitaire Ziekenhuizen Leuven (UZ Leuven)

    Leuven, B-3000, Belgium

  • University Hospital Schleswig-Holstein (UKSH) Campus Lübeck, Department for Neurology/ Precision Neurology

    Lübeck, Germany

  • University of Alberta

    Edmonton, Alberta, T6G 2G3, Canada

  • University of Calgary

    Calgary, Alberta, T2N 1N4, Canada

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

Conditions

Explore the condition pages connected to this study.