Body-Made CAR-T cells take on Hard-to-Treat myeloma

NCT ID NCT07539233

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests a new gene therapy called QI-019B for people with multiple myeloma that has returned or not responded to at least two prior treatments. The therapy works by creating cancer-fighting CAR-T cells directly inside the patient's body. The study will enroll 24 participants to check safety and see if the treatment shrinks tumors.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

QI-019B (a gene therapy that creates CAR-T cells inside the body)

What this could lead to

If it works, this could offer a new treatment option for people with multiple myeloma that has stopped responding to other therapies.

What could go wrong

This is a very early, small trial (24 people) focused on safety. The treatment may not work, and there are risks like severe immune reactions (cytokine release syndrome) and nerve problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institute of Hematology & Blood Diseases Hospital

    Tianjin, Tianjin Municipality, 300000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••