New drug shows promise for Tough-to-Treat blood cancers

NCT ID NCT05526313

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested a new drug called Purinostat Mesylate in 29 people with relapsed or refractory B-cell lymphomas, a type of blood cancer. The main goals were to check safety, find the right dose, and see how the drug moves through the body. Researchers hope this drug could offer a new option for patients who have run out of standard treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Purinostat Mesylate

What this could lead to

If successful, this could point toward a new treatment option for people with hard-to-treat B-cell lymphomas.

What could go wrong

This is a very early Phase 1 trial with only 29 participants, so safety and dosing are still being figured out. It may not lead to an effective treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

B-cell acute lymphoblastic leukemia B-cell neoplasm diffuse large B-cell lymphoma interdigitating dendritic cell sarcoma plasma cell myeloma T-cell acute lymphoblastic leukemia T-cell non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • West China Hospital Sichuan University

    Chengdu, Sichuan, 610000, China