Eye test may reveal new clues about sleep disorder

NCT ID NCT06949644

Recruiting now Knowledge-focused Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Apr 10, 2026 · Last updated May 15, 2026 · Updated 7 times

Summary

This study looks at how the pupils of people with delayed sleep-wake phase disorder react to light. Researchers want to see if there are differences in light sensitivity and whether a single dose of citalopram (a serotonin-boosting drug) can increase melatonin suppression during bright light exposure. About 220 adults with the disorder will do sleep and melatonin tests at home, then an eye exam. A smaller group will also have two overnight stays to measure melatonin levels after taking either citalopram or a placebo.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

DELAYED SLEEP-WAKE PHASE DISORDER