New hope for advanced kidney cancer: experimental drug combo enters trials

NCT ID NCT07293351

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests a new drug called pumitamig, alone or with other medicines (ipilimumab or cabozantinib), in people with advanced kidney cancer that has spread. The goal is to see if these combinations are safe and can shrink tumors or slow the disease. About 234 adults with clear cell or non-clear cell kidney cancer will take part. This is not a cure; it aims to control the cancer and manage symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Bradfordhill

    RECRUITING

    Santiago, Santiago Metropolitan, 8420383, Chile

    Contact Phone: •••-•••-••••

  • Carolina Urologic Research Center, LLC

    RECRUITING

    Myrtle Beach, South Carolina, 29572, United States

    Contact Phone: •••-•••-••••

  • GenesisCare St Leonards

    RECRUITING

    St Leonards, New South Wales, 2065, Australia

    Contact Phone: •••-•••-••••

  • HOCH Health Ostschweiz

    RECRUITING

    Sankt Gallen, 9007, Switzerland

    Contact Phone: •••-•••-••••

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-••••

  • Kantonsspital Graubünden

    RECRUITING

    Chur, 7000, Switzerland

    Contact Phone: •••-•••-••••

  • Local Institution - 0003

    NOT_YET_RECRUITING

    Malvern, 3144, Australia

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  • Local Institution - 0007

    NOT_YET_RECRUITING

    Calgary, Alberta, T2N 4N2, Canada

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  • Local Institution - 0009

    NOT_YET_RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

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  • Local Institution - 0013

    NOT_YET_RECRUITING

    Madrid, 28041, Spain

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  • Local Institution - 0014

    NOT_YET_RECRUITING

    Herne, 44649, Germany

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  • Local Institution - 0017

    NOT_YET_RECRUITING

    Seoul, Seoul-teukbyeolsi, 05505, South Korea

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  • Local Institution - 0025

    NOT_YET_RECRUITING

    Jena, Thuringia, 07747, Germany

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  • Local Institution - 0026

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    Hamburg, 20251, Germany

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  • Local Institution - 0027

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    München, 81675, Germany

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  • Local Institution - 0028

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    Villejuif, 94805, France

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  • Local Institution - 0029

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    Turku, 20521, Finland

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  • Local Institution - 0043

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    Seville, 41013, Spain

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  • Local Institution - 0044

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    Helsinki, Etelä-Suomen Lääni, 00290, Finland

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  • Local Institution - 0046

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    Monterrey, Nuevo León, 64040, Mexico

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  • Local Institution - 0048

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    Oaxaca City, 68020, Mexico

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  • Local Institution - 0049

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    Tlalpan, 14080, Mexico

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  • Local Institution - 0052

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    Cali, 760032, Colombia

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  • Local Institution - 0057

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    Cardiff, CF14 2TL, United Kingdom

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  • Local Institution - 0059

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    Dublin, D07 R2WY, Ireland

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  • Local Institution - 0060

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    Vantaa, 01640, Finland

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  • Local Institution - 0062

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    Dublin, D24 NR0A, Ireland

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  • Local Institution - 0073

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    Milan, 20133, Italy

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  • Local Institution - 0074

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    South Brisbane, Queensland, 4101, Australia

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  • Local Institution - 0076

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    North Ryde, New South Wales, 2109, Australia

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  • Local Institution - 0078

    NOT_YET_RECRUITING

    Toyoma, Toyama, 930-0194, Japan

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  • Local Institution - 0080

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    Boredeaux, 33076, France

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  • Local Institution - 0083

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    Lille, Nord, 59020, France

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  • Local Institution - 0087

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    Napoli Campania, 80131, Italy

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  • Local Institution - 0091

    NOT_YET_RECRUITING

    Madrid, 28050, Spain

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  • Local Institution - 0093

    NOT_YET_RECRUITING

    Brasília, Federal District, 70200-730, Brazil

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  • Local Institution - 0095

    NOT_YET_RECRUITING

    Seattle, Washington, 98109-1023, United States

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  • Local Institution - 0096

    NOT_YET_RECRUITING

    Hauppauge, New York, 11788, United States

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  • Local Institution - 0100

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    Iași, 700483, Romania

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  • Local Institution - 0101

    NOT_YET_RECRUITING

    Sibiu, 550082, Romania

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  • Local Institution - 0103

    NOT_YET_RECRUITING

    Cluj-Napoca, 400015, Romania

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  • Local Institution - 0105

    NOT_YET_RECRUITING

    Santiago, Santiago Metropolitan, 7510032, Chile

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  • Local Institution - 0108

    NOT_YET_RECRUITING

    Tlalpan, 14080, Mexico

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  • Local Institution - 0109

    NOT_YET_RECRUITING

    Montreal, Quebec, H2L 4M1, Canada

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  • Local Institution - 0112

    NOT_YET_RECRUITING

    Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea

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  • Local Institution - 0117

    NOT_YET_RECRUITING

    New Haven, Connecticut, 06510, United States

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  • Local Institution - 0118

    NOT_YET_RECRUITING

    Tlalpan, 14080, Mexico

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  • Local Institution - 0122

    NOT_YET_RECRUITING

    Puebla City, 72424, Mexico

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  • Local Institution - 0124

    NOT_YET_RECRUITING

    Iowa City, Iowa, 52242, United States

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  • Local Institution - 0126

    NOT_YET_RECRUITING

    Orlando, Florida, 32803, United States

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  • Local Institution - 0127

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

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  • Local Institution - 0135

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45219, United States

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  • Local Institution - 0139

    NOT_YET_RECRUITING

    Verona, Veneto, 37126, Italy

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  • Local Institution - 0147

    NOT_YET_RECRUITING

    Prague, Praha 5, 150 06, Czechia

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  • Local Institution - 0149

    NOT_YET_RECRUITING

    Brno, 656 53, Czechia

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  • Local Institution - 0150

    NOT_YET_RECRUITING

    Hradec Králové, 500 05, Czechia

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  • Local Institution - 0154

    NOT_YET_RECRUITING

    Buenos Aires, 1426, Argentina

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  • Local Institution - 0156

    NOT_YET_RECRUITING

    Buenos Aires, C1199ABB, Argentina

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  • Local Institution - 0158

    WITHDRAWN

    Salt Lake City, Utah, 84112, United States

  • Local Institution - 0161

    NOT_YET_RECRUITING

    Craiova, 200347, Romania

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  • Local Institution - 0163

    NOT_YET_RECRUITING

    Santiago, 8330023, Chile

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  • Local Institution - 0167

    NOT_YET_RECRUITING

    Seoul, 120-752, South Korea

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  • Local Institution - 0172

    NOT_YET_RECRUITING

    Fukuoka, 812-8582, Japan

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  • MUSC Hollings Cancer Center

    RECRUITING

    Charleston, South Carolina, 29425, United States

    Contact Phone: •••-•••-••••

  • Royal Marsden Hospital (Chelsea)

    RECRUITING

    London, Kensington and Chelsea, SW3 6JJ, United Kingdom

    Contact Phone: •••-•••-••••

  • Royal Marsden Hospital Sutton

    RECRUITING

    Sulton, Surrey, SM25PT, United Kingdom

    Contact Phone: •••-•••-••••

  • Sibley Memorial Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20016, United States

    Contact Phone: •••-•••-••••

  • St Bartholomew's Hospital

    RECRUITING

    London, London, City of, EC1A 7BE, United Kingdom

    Contact Phone: •••-•••-••••

  • The Cancer Institute Hospital of JFCR

    RECRUITING

    Koto-ku, Tokyo, 135-8550, Japan

    Contact Phone: •••-•••-••••

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-••••

  • UniversitätsSpital Zürich

    RECRUITING

    Zurich, 8091, Switzerland

    Contact Phone: •••-•••-••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.