Can a Pulse-Powered plate slow the clock on aging?
NCT ID NCT05577858
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers are testing whether a vegetarian diet built around pulses like beans, lentils, and chickpeas can improve health markers in adults aged 60 and older. Participants eat both a pulse-based diet and a meat-based diet following dietary guidelines, switching between them over 18 weeks. The study measures changes in gut bacteria, blood sugar, body composition, and hundreds of other health biomarkers to see how plant protein affects the body.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a lacto-ovo-vegetarian diet with pulses as the main protein source
- What this could lead to
- If it works, this could show that swapping meat for pulses supports healthier aging and lowers the risk of chronic disease in older adults.
- What could go wrong
- This is a small feeding study in healthy older adults, so the results may not apply to other age groups or people with existing conditions. Diet studies also struggle to separate the food itself from other lifestyle factors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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76 people
The number who actually took part.
- Started
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Nov 2022
- Finished
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Dec 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Generally good health status based on routine physical in the past 12 months, current healthy status * Normal HbA1C, not underweight * Age 60 years or more, all races, both sexes and all education level * Do not have any special dietary requirements and willing to consume vegetarian diet * Willingness to comply with the study protocol, including on-site meal consumption and sample/data collection. Exclusion Criteria: * Probiotic, long-term antibiotic, and tobacco/drug/alcohol use * Not on any special diet within 3 months of recruitment * Impaired kidney functions * Active history of cancer, diabetes, heart, liver, and kidney diseases * Major gastrointestinal disorders in the past 3 months * History of heart attacks or stroke * Unable to meet in-person visit requirements for dining, picking up meals, and tests * Any mental health condition that would affect the ability to provide written informed consent. * If they had not had a routine health checkup during the 12 months prior to recruitment. * If they were unwilling to abstain from taking certain nutritional supplements, alcohol, or non-study foods during the study period.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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South Dakota State University, Wagner Hall 416
Brookings, South Dakota, 57007, United States
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