Cancer combo trial halted early: did the STING agonist fall short?

NCT ID NCT05846646

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 31 times

Summary

This study tested whether adding an experimental drug called IMSA101 to a combination of targeted radiation (PULSAR) and standard immunotherapy could better control advanced lung or kidney cancer that had spread to a few spots. Only 6 people enrolled before the trial was stopped early. The goal was to see if the drug combo slowed cancer growth and was safe.

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Contacts and locations

Locations

  • Baylor College of Medicine Medical Center

    Houston, Texas, 77030, United States

  • City of Hope Orange County Lennar Foundation Cancer Center

    Irvine, California, 92618, United States

  • Huntsman Cancer Institute, University of Utah

    Salt Lake City, Utah, 84112, United States

  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health

    New York, New York, 10016, United States

  • Louis Stokes Cleveland VA Medical Center

    Cleveland, Ohio, 44106, United States

  • MetroHealth Medical Center

    Cleveland, Ohio, 44109, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • The University of Kansas Medical Center

    Kansas City, Kansas, 66160, United States

  • University of Wisconsin Hospital and Clinics

    Madison, Wisconsin, 53792, United States

Conditions

Explore the condition pages connected to this study.