Experimental combo therapy for advanced cancer shows promise but trial ends early
NCT ID NCT05846646
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new treatment for people with non-small cell lung cancer or kidney cancer that had spread to up to six spots in the body. The treatment combined a special type of radiation therapy (PULSAR) with immunotherapy drugs (pembrolizumab or nivolumab), with or without an experimental drug called IMSA101 that boosts the immune system. The goal was to see if adding IMSA101 made the treatment safer and more effective. The trial was stopped early after enrolling only 6 participants, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baylor College of Medicine Medical Center
Houston, Texas, 77030, United States
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City of Hope Orange County Lennar Foundation Cancer Center
Irvine, California, 92618, United States
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Huntsman Cancer Institute, University of Utah
Salt Lake City, Utah, 84112, United States
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Laura & Isaac Perlmutter Cancer Center at NYU Langone Health
New York, New York, 10016, United States
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Louis Stokes Cleveland VA Medical Center
Cleveland, Ohio, 44106, United States
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MetroHealth Medical Center
Cleveland, Ohio, 44109, United States
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Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
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The University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Wisconsin Hospital and Clinics
Madison, Wisconsin, 53792, United States