Precision radiation plus immunotherapy shows promise for bile duct cancer

NCT ID NCT07291947

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new approach for advanced bile duct cancer, combining a precise type of radiation (PULSAR) with immunotherapy drugs and chemotherapy. The goal is to see if this combination is safe and effective. The trial is recruiting 60 adults aged 18-75 with confirmed bile duct cancer that has spread.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Iparomlimab and Tuvonralimab Injection (QL1706) combined with chemotherapy and PULSAR radiation therapy

What this could lead to

If successful, this could offer a new treatment option for advanced bile duct cancer by combining precise radiation with immune-boosting drugs.

What could go wrong

This is an early-phase trial with only 60 participants, so results may not apply to all patients. The combination therapy may cause significant side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cholangiocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••