New hope for rare lung condition: experimental drug shows promise
NCT ID NCT00993408
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 33 times
Summary
This study tested an experimental drug called ACT-293987 in 43 adults with pulmonary arterial hypertension (PAH), a serious condition where high blood pressure damages the arteries in the lungs. Participants first received a single dose to measure immediate effects on blood flow, then took the drug or a placebo twice daily for 21 weeks. The goal was to see if the drug improves blood vessel function and exercise ability, while checking for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Department of Respiratory Medicine, Hannover Medical School
Hanover, 30625, Germany
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Gasthuisberg University Hospital, Pneumology
Leuven, 3000, Belgium
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Hammersmith Hospital
London, W12 0HS, United Kingdom
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Hopital Antoine Beclere, Pneumologie
Paris, France
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Hospital Sant'Orsola Malpighi, Cardiology's Department
Bologna, 40138, Italy
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Instytut Gruzilcy i Chorob Pluc, Klinika Chorob Wewnetrznych Klatki Piersiowej
Warsaw, 01-138, Poland
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Medizinische Universitat Wien, Universitatsklinik fur Innere Medizin II, Kardiologie
Vienna, 1090, Austria
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Semmelweis University, Clinic of Pulmonology
Budapest, H-1125, Hungary
Conditions
Explore the condition pages connected to this study.