Can common sleep aids finally help veterans with PTSD-Related insomnia?
NCT ID NCT03668041
First seen Nov 06, 2025 · Last updated Apr 24, 2026 · Updated 23 times
Summary
This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD and insomnia. The goal was to see if these drugs could improve sleep quality over 12 weeks. Researchers measured changes using the Insomnia Severity Index and also tracked PTSD symptoms.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Asheville VA Medical Center, Asheville, NC
Asheville, North Carolina, 28805, United States
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Atlanta VA Medical and Rehab Center, Decatur, GA
Decatur, Georgia, 30033, United States
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Bay Pines VA Healthcare System, Pay Pines, FL
Bay Pines, Florida, 33744-0000, United States
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Birmingham VA Medical Center, Birmingham, AL
Birmingham, Alabama, 35233, United States
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CERC (VISN1, West Haven, CT)
West Haven, Connecticut, 06516, United States
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Cincinnati VA Medical Center, Cincinnati, OH
Cincinnati, Ohio, 45220-2213, United States
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Clement J. Zablocki VA Medical Center, Milwaukee, WI
Milwaukee, Wisconsin, 53295-0001, United States
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Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA
Philadelphia, Pennsylvania, 19104, United States
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Durham VA Medical Center, Durham, NC
Durham, North Carolina, 27705-3875, United States
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Edward Hines Jr. VA Hospital, Hines, IL
Hines, Illinois, 60141-3030, United States
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Louis Stokes VA Medical Center, Cleveland, OH
Cleveland, Ohio, 44106, United States
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Michael E. DeBakey VA Medical Center, Houston, TX
Houston, Texas, 77030-4211, United States
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Minneapolis VA Health Care System, Minneapolis, MN
Minneapolis, Minnesota, 55417, United States
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New Mexico VA Health Care System, Albuquerque, NM
Albuquerque, New Mexico, 87108-5153, United States
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Overton Brooks VA Medical Center, Shreveport, LA
Shreveport, Louisiana, 71101, United States
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Phoenix VA Health Care System, Phoenix, AZ
Phoenix, Arizona, 85012, United States
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Providence VA Medical Center, Providence, RI
Providence, Rhode Island, 02908, United States
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Ralph H. Johnson VA Medical Center, Charleston, SC
Charleston, South Carolina, 29401-5799, United States
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Salem VA Medical Center, Salem, VA
Salem, Virginia, 24153, United States
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Salisbury W.G. (Bill) Hefner VA Medical Center, Salisbury, NC
Salisbury, North Carolina, 28144, United States
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San Francisco VA Medical Center, San Francisco, CA
San Francisco, California, 94121-1563, United States
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South Texas Health Care System, San Antonio, TX
San Antonio, Texas, 78229, United States
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Tuscaloosa VA Medical Center, Tuscaloosa, AL
Tuscaloosa, Alabama, 35404, United States
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VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA
Boston, Massachusetts, 02130-4817, United States
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VA Connecticut Healthcare System West Haven Campus, West Haven, CT
West Haven, Connecticut, 06516-2770, United States
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VA Loma Linda Healthcare System, Loma Linda, CA
Loma Linda, California, 92357-1000, United States
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VA Long Beach Healthcare System, Long Beach, CA
Long Beach, California, 90822, United States
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VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX
Dallas, Texas, 75216-7167, United States
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VA Palo Alto Health Care System, Palo Alto, CA
Palo Alto, California, 94304-1207, United States
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VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
Pittsburgh, Pennsylvania, 15240, United States
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VA Puget Sound Health Care System Seattle Division, Seattle, WA
Seattle, Washington, 98108, United States
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VA Salt Lake City Health Care System, Salt Lake City, UT
Salt Lake City, Utah, 84148, United States
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VA San Diego Healthcare System, San Diego, CA
San Diego, California, 92161, United States
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White River Junction VA Medical Center, White River Junction, VT
White River Junction, Vermont, 05009-0001, United States
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William S. Middleton Memorial Veterans Hospital, Madison, WI
Madison, Wisconsin, 53705, United States
Conditions
Explore the condition pages connected to this study.