New psoriatic arthritis drug shows promise in Mid-Stage trial
NCT ID NCT07321873
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times
Summary
This study tests whether the experimental drug JNJ-88545223 can reduce joint pain, swelling, and skin symptoms in adults with active psoriatic arthritis. About 240 participants will receive either the drug or a placebo to see if it works better than no treatment. The goal is to improve joint and skin health over 16 weeks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Albuquerque Rehabilitation and Rheumatology
RECRUITINGAlbuquerque, New Mexico, 87102, United States
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American Research, LLC
RECRUITINGCutler Bay, Florida, 33157, United States
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Arthritis and Rheumatology Research Institute
RECRUITINGFrisco, Texas, 75035, United States
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Atlanta Research Center for Rheumatology
RECRUITINGMarietta, Georgia, 30060, United States
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Beijing Tsinghua Changgung Hospital
RECRUITINGBeijing, 102218, China
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Bekes Varmegyei Kozponti Korhaz Pandy Kalman Tagkorhaz
RECRUITINGGyula, 5700, Hungary
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CAIR Heidelberg
RECRUITINGHeidelberg, 69121, Germany
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Centrum Kliniczno Badawcze
RECRUITINGElblag, 82-300, Poland
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Centrum Medyczne Reuma Park
RECRUITINGWarsaw, 02 665, Poland
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Changzhou No 2 Peoples Hospital
RECRUITINGChangzhou, 213003, China
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Charite Universitaetsmedizin Berlin
RECRUITINGBerlin, 10117, Germany
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Clinical Research Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19114, United States
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Clinical Research of West Florida
RECRUITINGTampa, Florida, 33606, United States
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Clintrial s r o
RECRUITINGPrague, 100 00, Czechia
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Complex Rendelo Med Zrt
RECRUITINGSzékesfehérvár, 8000, Hungary
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Conquest Research
RECRUITINGWinter Park, Florida, 32789, United States
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ETG Lublin
RECRUITINGLublin, 20 412, Poland
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Etyka Osrodek Badan Klinicznych Tomasz Pesta S K A
RECRUITINGOlsztyn, 10 117, Poland
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Fachklinik Bad Bentheim
RECRUITINGBad Bentheim, 48455, Germany
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FutureMeds Targowek
RECRUITINGWarsaw, 03 291, Poland
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Gemeinschaftspraxis Dres. Quist
RECRUITINGMainz, 55128, Germany
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Hamburger Rheuma Forschungszentrum II
RECRUITINGHamburg, 20095, Germany
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Hautarztpraxis
RECRUITINGWitten, 58453, Germany
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Hautarztpraxis Mortazawi
RECRUITINGRemscheid, 42897, Germany
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Hosp Univ A Coruna
RECRUITINGA Coruña, 15006, Spain
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Hosp. Clinico Univ. de Santiago
RECRUITINGSantiago de Compostela, 15706, Spain
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Hosp. Infanta Luisa
RECRUITINGSeville, 41010, Spain
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Hosp. Virgen Del Rocio
RECRUITINGSeville, 41013, Spain
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Hosp. Virgen Macarena
RECRUITINGSeville, 41009, Spain
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Hospital of the University of Occupational and Environmental Health
RECRUITINGKitakyushu-shi, 807-8556, Japan
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Imamura General Hospital
RECRUITINGKagoshima, 890-0064, Japan
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Innovation Medical Research Center
RECRUITINGPalmetto Bay, Florida, 33157, United States
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Integral Rheumatology And Immunology Specialists
RECRUITINGPlantation, Florida, 33324, United States
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Joint and Muscle Research Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
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L K N Arthrocentrum
RECRUITINGHlučín, 748 01, Czechia
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MICS Centrum Medyczne Torun
RECRUITINGTorun, 87-100, Poland
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MICS Centrum Medyczne Warszawa
RECRUITINGWarsaw, 00 874, Poland
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MICS Centrum Medyczne Warszawa 1
RECRUITINGWarsaw, 00-872, Poland
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Malopolskie Badania Kliniczne Sp z o o
RECRUITINGKrakow, 30-002, Poland
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Medical Plus Research S R O
RECRUITINGUherské Hradiště, 68601, Czechia
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NZOZ Lecznica MAK MED S C
RECRUITINGNadarzyn, 05-830, Poland
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Newport Huntington Medical Group
RECRUITINGHuntington Beach, California, 92648, United States
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Ningbo medical center lihuili hospital
RECRUITINGNingbo, 315041, China
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Nzoz Osteo Medic
RECRUITINGBialystok, 15 351, Poland
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Obudai Egeszsegugyi Centrum Kft
RECRUITINGBudapest, 1036, Hungary
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Osaka Metropolitan University Hospital
RECRUITINGOsaka, 545 8586, Japan
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Paramount Medical Research & Consulting
RECRUITINGMiddleburg Heights, Ohio, 44130, United States
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Peking University People's Hospital
RECRUITINGBeijing, 100044, China
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Peking University Third Hospital
RECRUITINGBeijing, 100191, China
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Porcika Klinika - Vasarhelyi Sarkanyfu Kft.
RECRUITINGHódmezővásárhely, 6800, Hungary
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Pratia Czech A S
RECRUITINGPardubice, 53002, Czechia
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Pratia MCM Krakow
RECRUITINGKrakow, 30-727, Poland
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Praxis Mario Sutowicz
RECRUITINGCottbus, 3042, Germany
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Qualiclinic Kft
RECRUITINGBudapest, 1134, Hungary
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Qualmedica Research
RECRUITINGEvansville, Indiana, 47715, United States
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RHEUMA s r o
RECRUITINGBřeclav, 690 02, Czechia
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Revmatologicka ambulance
RECRUITINGKarvina Frystat, 733 01, Czechia
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Rheuma Medicus Sp z o o
RECRUITINGWarsaw, 02 118, Poland
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Rheumatologische Schwerpunktpraxis
RECRUITINGBerlin, 10777, Germany
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Rheumatology Center of San Diego
RECRUITINGSan Diego, California, 92128, United States
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Sanuki Municipal Hospital
RECRUITINGSanuki, 769-2393, Japan
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Semmelweis Egyetem Reumatologiai es Immunologiai Klinika
RECRUITINGBudapest, 1023, Hungary
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Shanghai Sixth People's Hospital
RECRUITINGShanghai, 200233, China
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Szpital Uniwersytecki nr 2 im dr Jana Biziela w Bydgoszczy
RECRUITINGBydgoszcz, 85 168, Poland
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The First Affiliated Hospital of Chongqing Medical University
RECRUITINGChongqing, 400016, China
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The Second Affiliated Hospital of Zhejiang University
RECRUITINGHangzhou, 310009, China
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Tokito Clinic Rheumatology and Orthopaedic Surgery
RECRUITINGShimonoseki, 752 0976, Japan
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Tokyo Metropolitan Tama Medical Center
RECRUITINGFuchū, 183 8524, Japan
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Unity Health-White County Medical Center
RECRUITINGSearcy, Arkansas, 72143, United States
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Vital Medical Center Orvosi es Fogaszati Kozpont
RECRUITINGVeszprém, 8200, Hungary
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West China Hospital Sichuan University
RECRUITINGChengdu, 610093, China
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Willow Rheumatology and Wellness PLLC
RECRUITINGWillowbrook, Illinois, 60527, United States
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Xiangya Hospital Central South University
RECRUITINGChangsha, 410008, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- New study to measure drug levels in breast milk of moms on TREMFYA
- New drug shows promise in taming psoriatic arthritis flares
- New injection targets psoriatic arthritis pain in small trial
- New study tracks arthritis drug persistence in daily life
- Scientists probe hidden pain pathways in arthritis
- New drug combo shows promise for Tough-to-Treat psoriatic arthritis