New imaging agent could sharpen prostate cancer staging

NCT ID NCT03535831

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed registry study at Princess Margaret Cancer Centre tested whether a special PET scan tracer called 18F-DCFPyL (PSMA) can find prostate cancer that has spread to lymph nodes or other organs better than standard CT and bone scans. A total of 142 men with intermediate- or high-risk prostate cancer, or those with a rising PSA after treatment, received a PSMA PET scan. The goal was to see if this imaging method changes how doctors stage or restage the disease and guides treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

18F-DCFPyL (a radioactive tracer used in PET scans)

What this could lead to

If successful, this imaging method could help doctors find prostate cancer spread more accurately, leading to better treatment decisions.

What could go wrong

This is a registry study, not a randomized trial, so results may not prove that PSMA PET improves patient outcomes. The sample size is modest (142 men), and findings may not apply to all prostate cancer patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

prostate cancer prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada