Magic mushrooms vs ketamine: a new hope for heavy drinkers?

NCT ID NCT05421065

First seen Nov 17, 2025 · Last updated Apr 30, 2026 · Updated 22 times

Summary

This pilot study tests whether psilocybin (magic mushrooms) or ketamine, combined with talk therapy, can help men aged 25-65 with moderate to severe alcohol use disorder drink less. Twenty participants will receive one of the two treatments and be tracked for changes in drinking habits and brain activity. The goal is to gather early data on which approach works better for controlling alcohol cravings and consumption.

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Contacts and locations

Locations

  • University of Iowa

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.