Psychedelic showdown: can psilocybin or ketamine help men stop heavy drinking?

NCT ID NCT05421065

First seen Nov 17, 2025 · Last updated Jun 11, 2026 · Updated 26 times

Summary

This small study tests whether psilocybin or ketamine, combined with talk therapy, can help men aged 25-65 reduce heavy drinking. Participants must have moderate to severe alcohol use disorder and at least 4 heavy drinking days per month. The study tracks alcohol use and brain changes using scans.

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Contacts and locations

Locations

  • University of Iowa

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.