Magic mushroom therapy targets tough depression and addiction in heroes

NCT ID NCT07499583

First seen Apr 01, 2026 · Last updated Jun 16, 2026 · Updated 19 times

Summary

This study tests whether a single dose of psilocybin (5, 10, or 25 mg) combined with psychotherapy is safe and can reduce depression and substance use in veterans and first responders with treatment-resistant depression and substance use disorder. Over 14 weeks, 50 participants will receive therapy sessions, brain scans, and daily assessments. The goal is to see if this approach eases symptoms and changes brain activity.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Goodman Hall, Dept of Psychiatry, Indiana University

    Indianapolis, Indiana, 46202-3082, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • The Stark Neuroscience Building (Goodman Hall)

    Indianapolis, Indiana, 46202, United States

Conditions

Explore the condition pages connected to this study.