Scientists to test if blocking the psychedelic 'Trip' kills the benefits

NCT ID NCT06768944

First seen Jan 08, 2026 · Last updated May 10, 2026 · Updated 17 times

Summary

This study looks at whether the intense, subjective experience (the 'trip') caused by psilocybin, the active ingredient in magic mushrooms, is necessary for its positive after-effects. Researchers will give 128 healthy adults psilocybin along with either a placebo or risperidone, a drug that blocks the psychedelic effects. By comparing the two groups, they hope to understand if the subjective experience itself is key to any lasting positive changes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Calgary

    Calgary, Alberta, T2N 4N1, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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