Magic mushrooms vs. depression: new trial tests combo with prozac

NCT ID NCT06898606

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study tests whether taking psilocybin mushrooms (the active ingredient in magic mushrooms) along with the antidepressant fluoxetine (Prozac) is safe and helps reduce depression symptoms. 24 adults with treatment-resistant depression will receive one dose of mushrooms and either fluoxetine or a placebo. The main goal is to see how depression scores change over 4 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Federal University of Latin American Integration

    RECRUITING

    Foz do Iguaçu, Paraná, 85870-650, Brazil

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.