Magic mushroom compound shows promise for tough depression
NCT ID NCT03554174
First seen Nov 05, 2025 · Last updated May 24, 2026 · Updated 22 times
Summary
This small study tests whether psilocybin, the active ingredient in magic mushrooms, can change how the brain adapts and grows (neuroplasticity) in people with major depression. 18 adults who haven't gotten better with standard antidepressants will receive psilocybin in a controlled setting. Researchers will measure brain activity and memory changes to see if these brain changes link to mood improvement.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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VA Connecticut Healthcare System, West Haven Campus
West Haven, Connecticut, 06516, United States
Conditions
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