Magic mushroom compound shows promise for tough depression
NCT ID NCT03554174
First seen Nov 05, 2025 · Last updated Jun 15, 2026 · Updated 26 times
Summary
This early-stage study tests whether psilocybin, the active ingredient in magic mushrooms, can change brain connections to improve depression. 18 adults with major depression who didn't get better with standard treatments will receive psilocybin in a controlled setting. Researchers will measure brain activity and memory changes to see if psilocybin helps the brain become more flexible.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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VA Connecticut Healthcare System, West Haven Campus
West Haven, Connecticut, 06516, United States
Conditions
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