New radiation therapy shows promise against hard-to-treat gut and pancreas cancers

NCT ID NCT03049189

First seen Apr 07, 2026 · Last updated Apr 30, 2026 · Updated 5 times

Summary

This study tests a new type of radiation therapy (PRRT with 177Lu-Edotreotide) against a standard targeted drug (everolimus) in people with advanced neuroendocrine tumors that have spread and can't be removed by surgery. About 324 participants will be randomly assigned to one of the two treatments. The main goal is to see which treatment better delays tumor growth or death.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEUROENDOCRINE TUMORS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • "Gammed" Izabela Chuchrowksa

    Warsaw, 02-351, Poland

  • Academic Medical Center, University of Amsterdam

    Amsterdam, 1100DD, Netherlands

  • Allgemeines Krankenhaus Wien

    Vienna, 1090, Austria

  • Banner Health d.b.a. Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • CHU de Nantes - Hôtel Dieu

    Nantes, 44093, France

  • Central University Hospital de Asturias (HUCA)

    Oviedo, 33011, Spain

  • Centre Jean Perrin

    Clermont-Ferrand, 63011, France

  • Charité - Universitätsmedizin Berlin

    Berlin, 10117, Germany

  • European Institute of Oncology (EIO)

    Milan, 20141, Italy

  • Excel Diagnostics & Nuclear Oncology Center

    Houston, Texas, 77042, United States

  • Fiona Stanley Hospital

    Murdoch, Western Australia, 6150, Australia

  • Fondazione IRCCS Istituto Nazionale dei Tumori

    Milan, 20133, Italy

  • HP Hôpital Beaujon

    Clichy, 92110, France

  • Hospices civils de Lyon

    Bron, 69677, France

  • ICO Hospitalet, Granvia de l'Hospitalet

    Barcelona, 08909, Spain

  • IUCT-Oncopole

    Toulouse, 31059, France

  • Inselspital, Universitätsspital Bern

    Bern, 3010, Switzerland

  • Institut Jules Bordet

    Brussels, 1000, Belgium

  • Institut de Recherche en Cancérologie de Montpellier (IRCM)

    Montpellier, 34298, France

  • Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) Srl

    Meldola, 47014, Italy

  • Kings College Hospital

    London, SE5 9RS, United Kingdom

  • Klinikum rechts der Isar Technische Universität München

    Munich, 81675, Germany

  • MD Anderson Cancer Center Madrid

    Madrid, 28033, Spain

  • MSC Memorial Cancer Centre

    Gliwice, 44-100, Poland

  • Moffitt Cancer Center & Research Institute

    Tampa, Florida, 33612, United States

  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

  • Olivia Newton-John Cancer & Wellness Centre, Austin Hospital

    Heidelberg, Victoria, 3084, Australia

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Philipps Universität Marburg

    Marburg, 35043, Germany

  • Royal Free NHS Foundation Trust

    London, NW3 2QG, United Kingdom

  • Royal North Shore Hospital

    Saint Leonards, New South Wales, 2065, Australia

  • Stanford University

    Stanford, California, 94305, United States

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • Universitaire Ziekenhuizen Leuven

    Leuven, 3000, Belgium

  • University Cape Town (UCT), Groote Schuur Hospital

    Cape Town, 7925, South Africa

  • University Hospital 12 de Octubre

    Madrid, 28041, Spain

  • University Hospital Motol

    Prague, 150 06, Czechia

  • University Hospital Olomouc

    Olomouc, 775 20, Czechia

  • University Medical Center, Abteilung für Nuklearmedizin

    Hamburg, 20251, Germany

  • University and Polytechnic Hospital La Fe

    Valencia, 46026, Spain

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Pretoria & Steve Biko Academic Hospital

    Pretoria, 0001, South Africa

  • UniversitätsSpital Zürich

    Zurich, 8091, Switzerland

  • Universitätsklinikum Bonn

    Bonn, 53127, Germany

  • Universitätsklinikum Erlangen

    Erlangen, 91054, Germany

  • Universitätsklinikum Essen

    Essen, 45147, Germany

  • Universitätsklinikum Magdeburg A.ö.R., Otto-von-Guericke Universität

    Magdeburg, 39120, Germany

  • Universitätsklinikum Ulm

    Ulm, 89081, Germany

  • Universitätsklinikum Würzburg

    Würzburg, 97080, Germany

  • Universitätsspital Basel

    Basel, 4031, Switzerland

  • Vall d'Hebron University Hospital

    Barcelona, 08035, Spain

  • Zentralklinik Bad Berka GmbH

    Bad Berka, 99437, Germany

Conditions

Explore the condition pages connected to this study.