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Blood-Based injection may offer new hope for chronic back pain without burning nerves

NCT ID NCT07692737

Symptom relief Sponsor: The New England Baptist Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study compares two treatments for chronic lower back pain caused by the small joints in the spine (facet joints). One treatment uses a person's own concentrated blood platelets (PRP) injected into the painful joint, while the other is a standard procedure that uses heat to disable the nerves sending pain signals (radiofrequency ablation). The trial enrolls 30 adults whose pain is confirmed to come from these joints. The goal is to see which approach provides better pain relief and function, and to gather information for larger future studies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Platelet-rich plasma (PRP) injection
What this could lead to
If PRP works as well or better than the standard procedure, it could offer a less invasive, injection-based option for chronic back pain without nerve burning.
What could go wrong
This is a small pilot study with only 30 participants, so results may not apply broadly. PRP is still experimental for this use, and pain relief may be temporary or no better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults with chronic lumbar back pain suspected to be facet-mediated * ≥80% pain relief following two diagnostic medial branch blocks * Ability to provide informed consent * Ability to complete patient-reported outcome measures Exclusion Criteria: * Active radiculopathy or alternate dominant spinal pain generator * Prior lumbar fusion at target level * Active systemic infection or local infection at injection site * Thrombocytopenia, less than 100,000/uL * Anemia, Hemoglobin less than 10 g/dL * Pregnancy * Inability to complete follow-up assessments

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic lower back pain (CLBP) Lumbar facet joint pain

How to take part

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  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Study contacts

  • Contact

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