Can your own blood ease nerve pain after disc surgery?
NCT ID NCT07770750
First seen Aug 18, 2026 · Last updated Aug 18, 2026
Summary
This study tests whether injecting platelet-rich plasma (PRP) into the epidural space during endoscopic disc herniation surgery can reduce nerve pain in the leg. PRP is made from the patient's own blood and may help healing and reduce inflammation. The trial will enroll 50 adults with a single-level lumbar disc herniation who have not improved with conservative treatment. Participants will receive the PRP injection during surgery and complete questionnaires to assess neuropathic pain over six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Platelet-rich plasma (PRP) injected into the epidural space during endoscopic disc removal
- What this could lead to
- If it works, this could point toward a way to reduce lingering nerve pain and improve recovery after disc herniation surgery.
- What could go wrong
- This is a small exploratory study, so results may not apply broadly. PRP is generally safe, but there is a small risk of infection or increased pain at the injection site.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Privé Jean Mermoz
Lyon, 69008, France