New proton therapy strategy aims to shrink side effects for young brain tumor patients
NCT ID NCT01419067
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether using limited surgery followed by proton therapy can control craniopharyngioma, a rare brain tumor, in children and young adults. The goal is to reduce radiation side effects by using a tighter radiation margin. Some patients who have complete tumor removal by surgery are simply watched without radiation. The trial tracks how long patients stay free of tumor growth and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
proton therapy
What this could lead to
If successful, this approach could offer a way to control craniopharyngioma with fewer long-term side effects than standard radiation.
What could go wrong
This is a phase II trial with a moderate number of participants, so results may not apply to everyone. There is still a risk of tumor progression or side effects from treatment.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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St. Jude Children's Research Hospital
Memphis, Tennessee, 38105, United States
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University of Florida Health Proton Therapy Institute
Jacksonville, Florida, 32206, United States