Proton beam therapy tested for rare spine and skull base tumors
NCT ID NCT01449149
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested proton beam therapy in 54 adults with chordomas or chondrosarcomas, rare tumors of the skull base and spine. The goal was to see if this precise radiation approach is feasible and safe, and to track both short- and long-term side effects. Researchers monitored how well patients tolerated treatment and whether serious side effects occurred within 90 days or later.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Proton beam therapy
- What this could lead to
- If successful, this could show that proton therapy is a safe and effective way to treat chordomas and chondrosarcomas, potentially improving tumor control with fewer side effects.
- What could go wrong
- This is a small, early-phase study with only 54 participants. It focuses on feasibility and safety, not yet proving long-term effectiveness. There is still a risk of serious side effects or the treatment not working as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
-
Abramson Cancer Center of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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