Precision radiation aims to spare kids from harsh side effects

NCT ID NCT03810651

Recruiting now Symptom relief Sponsor: Children's Hospital of Philadelphia Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a precise form of radiation called proton beam therapy for children and young adults with kidney tumors like Wilms tumor. The goal is to see if this approach causes fewer short-term side effects compared to standard radiation. About 28 participants will receive the treatment and be monitored for 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proton beam radiation therapy
What this could lead to: If successful, this approach could reduce short-term side effects of radiation for children with kidney tumors, making treatment safer.
What could go wrong: This is a very early pilot study with only 28 participants, so results may not apply to all patients. The therapy may still cause side effects.

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Conditions

The condition(s) this trial relates to.

clear cell sarcoma of kidney kidney neoplasm renal cell carcinoma Wilms tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL TUMOR WILMS TUMOR

Contacts and locations

Locations

Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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