New combo could cut hormone therapy time for prostate cancer patients
NCT ID NCT07550517
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a radioactive drug called 177Lu-PSMA-617 to standard radiation therapy can allow men with high-risk localized prostate cancer to take hormone therapy for only 6 months instead of the usual 24 months. The goal is to see if this approach is as effective at controlling cancer while reducing side effects from long-term hormone treatment. The trial will enroll 60 men and compare the two treatment plans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
177Lu-PSMA-617 (a radioactive drug that targets prostate cancer cells)
What this could lead to
If successful, this could allow men with high-risk prostate cancer to receive a shorter course of hormone therapy (6 months instead of 24 months), reducing side effects like hot flashes and bone loss while maintaining cancer control.
What could go wrong
This is a small, early-phase (phase 2) trial with only 60 participants. The experimental drug may not work as well as the standard long-term hormone therapy, and there is a risk of side effects from the radioactive drug, such as dry mouth or kidney issues.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Johns Hopkins University
Baltimore, Maryland, 21287, United States