New combo therapy targets tough prostate cancer

NCT ID NCT07319871

First seen Jan 11, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This early-stage study tests a new drug combination for men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. The treatment uses a T-cell redirecting agent (pasritamig) plus an A2a receptor blocker to help the immune system attack cancer cells. About 40 participants will be enrolled to find the safest dose and check for side effects.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Medical Center

    RECRUITING

    New York, New York, 10032, United States

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • The Christie NHS Foundation Trust Christie Hospital

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

Conditions

Explore the condition pages connected to this study.