New hope for prostate cancer: major trial tests drug combo to delay disease progression

NCT ID NCT07028853

Recruiting now Disease control Sponsor: Pfizer Source: ClinicalTrials.gov ↗

Summary

This study aims to see if adding an experimental drug called mevrometostat to the standard treatment enzalutamide works better for men with metastatic prostate cancer that still responds to hormone therapy. It will involve about 1,000 participants who have not yet received certain other treatments for this stage of their cancer. The main goal is to see if the combination can delay cancer growth longer and help patients live longer.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AdventHealth Medical Group Urology of Denver
NOT_YET_RECRUITING

Denver, Colorado, 80210, United States
Althaia, Xarxa Assistencial Universitària de Manresa
NOT_YET_RECRUITING

Manresa, Barcelona, 08243, Spain
Asan Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 05505, South Korea
Asociación de Beneficencia Hospital Sirio Libanés
NOT_YET_RECRUITING

Ciudad Autonoma de Buenos Aires, Buenos Aires, C1419AHN, Argentina
Beijing Friendship Hospital Affiliate of Capital University
RECRUITING

Beijing, Beijing Municipality, 100050, China
Blue Ridge Cancer Care
RECRUITING

Blacksburg, Virginia, 24060, United States
Blue Ridge Cancer Care
RECRUITING

Low Moor, Virginia, 24457, United States
Blue Ridge Cancer Care
RECRUITING

Roanoke, Virginia, 24014, United States
Blue Ridge Cancer Care
RECRUITING

Salem, Virginia, 24153, United States
Blue Ridge Cancer Care
RECRUITING

Wytheville, Virginia, 24382, United States
CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia
NOT_YET_RECRUITING

Santo André, São Paulo, 09060-870, Brazil
CHUVI- Hospital Alvaro Cunqueiro
NOT_YET_RECRUITING

Vigo, Pontevedra [pontevedra], 36212, Spain
Cancer Care Specialists of Illinois
RECRUITING

Decatur, Illinois, 62526, United States
Cancer Care Specialists of Illinois
RECRUITING

O'Fallon, Illinois, 62269, United States
Canisius-Wilhelmina Ziekenhuis
NOT_YET_RECRUITING

Nijmegen, Gelderland, 6532 SZ, Netherlands
Carolina Urologic Research Center, LLC
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
Centre Hospitalier de l'Université de Montréal
NOT_YET_RECRUITING

Montreal, Quebec, H2X 3E4, Canada
Centre Hospitalier de la Côte Basque
NOT_YET_RECRUITING

Bayonne, Pyrénées-atlantiques, 64109, France
Centre Intégré de Santé et de Services Sociaux de la Montérégie-Centre
RECRUITING

Greenfield Park, Quebec, J4V 2H1, Canada
Centre Leon Berard
NOT_YET_RECRUITING

Lyon Cedex08, Auvergne-Rhône-Alpes, 69373, France
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus
NOT_YET_RECRUITING

Québec, Quebec, G1J 1Z4, Canada
Centre intégré universitaire de santé et de services sociaux de l'Estrie - Centre Hospitalier Univer
RECRUITING

Sherbrooke, Quebec, J1H 5N4, Canada
Centre of Applied Urology Research/Nova Scotia Health Authority
RECRUITING

Halifax, Nova Scotia, B3H 2Y9, Canada
Centro Oncologico Korben
NOT_YET_RECRUITING

Buenos Aires, C1426ANZ, Argentina
Centrum Medyczne MEDYK
NOT_YET_RECRUITING

Rzeszów, 35-326, Poland
Chiba cancer center
RECRUITING

Chiba, Chiba, 260-8717, Japan
Chongqing University Cancer Hospital
RECRUITING

Chongqing, Chongqing Municipality, 400030, China
Chonnam National University Hwasun Hospital
RECRUITING

Hwasun-gun, Jeonranamdo, 58128, South Korea
Chungnam national university hospital
RECRUITING

Junggu, Taejǒn-kwangyǒkshi, 35015, South Korea
Clinical Best Solutions Sp. z o.o. S.K.
RECRUITING

Lublin, 20-011, Poland
Clinical Research Center Spółka z ograniczoną odpowiedzialnością MEDIC-R Sp.k
RECRUITING

Poznan, Greater Poland Voivodeship, 61-731, Poland
Complex Oncology Center - Plovdiv EOOD
NOT_YET_RECRUITING

Plovdiv, 4004, Bulgaria
Diex Recherche Trois-Rivieres
RECRUITING

Trois-Rivières, Quebec, G9A 4P3, Canada
EMC Instytut Medyczny S.A.
NOT_YET_RECRUITING

Wroclaw, 54-239, Poland
Ewha Womans University Mokdong Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 07985, South Korea
Fakultni Thomayerova nemocnice
NOT_YET_RECRUITING

Prague, 140 59, Czechia
Fakultni nemocnice Hradec Kralove
NOT_YET_RECRUITING

Hradec Králové, 500 03, Czechia
Fakultni nemocnice v Motole
NOT_YET_RECRUITING

Prague, 150 06, Czechia
First Huai'an Hospital Affiliated to Nanjing Medical University
RECRUITING

Huai'an, Jiangsu, 223300, China
Fudan University Shanghai Cancer Center
RECRUITING

Shanghai, Shanghai Municipality, 200032, China
Fundación Instituto Valenciano de Oncología
NOT_YET_RECRUITING

Valencia, Valenciana, Comunitat, 46009, Spain
Grand Strand Medical Center
RECRUITING

Myrtle Beach, South Carolina, 295724607, United States
Guy's & St Thomas' NHS Foundation Trust
NOT_YET_RECRUITING

London, London, CITY of, SE1 9RT, United Kingdom
Hadassah Medical Center
RECRUITING

Jerusalem, Jerusalem, 9112001, Israel
Highlands Oncology Group, PA
RECRUITING

Fayetteville, Arkansas, 72703, United States
Highlands Oncology Group, PA
RECRUITING

Rogers, Arkansas, 72758, United States
Highlands Oncology Group, PA
RECRUITING

Springdale, Arkansas, 72762, United States
Hokkaido University Hospital
RECRUITING

Sapporo, Hokkaido, 060-8648, Japan
Hospital Clinico San Carlos
NOT_YET_RECRUITING

Madrid, 28040, Spain
Hospital Clínic de Barcelona
NOT_YET_RECRUITING

Barcelona, Catalunya [cataluña], 08036, Spain
Hospital Universitario Ramón y Cajal
RECRUITING

Madrid, Madrid, Comunidad de, 28034, Spain
Hospital Universitario Virgen de la Victoria
NOT_YET_RECRUITING

Málaga, Málaga, 29010, Spain
Hunan Cancer Hospital
RECRUITING

Changsha, Hunan, 410013, China
Huntsman Cancer Institute
RECRUITING

Salt Lake City, Utah, 84112, United States
ICON Cancer Centre - Kurralta Park
NOT_YET_RECRUITING

Kurralta Park, South Australia, 5037, Australia
Icon Cancer Centre Chermside
NOT_YET_RECRUITING

Chermside, Queensland, 4032, Australia
Imperial College Healthcare NHS Trust, Charing Cross Hospital
RECRUITING

London, Hammersmith and Fulham, W6 8RF, United Kingdom
Inselspital Bern
NOT_YET_RECRUITING

Bern, Canton of Bern, 3010, Switzerland
Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
NOT_YET_RECRUITING

Bordeaux, Aquitaine, 33076, France
Ironwood Cancer & Research Centers
RECRUITING

Chandler, Arizona, 85224, United States
Ironwood Cancer & Research Centers
RECRUITING

Gilbert, Arizona, 85297, United States
Ironwood Cancer & Research Centers
RECRUITING

Glendale, Arizona, 85306, United States
Ironwood Cancer & Research Centers
RECRUITING

Goodyear, Arizona, 85395, United States
Ironwood Cancer & Research Centers
RECRUITING

Mesa, Arizona, 85202, United States
Ironwood Cancer & Research Centers
RECRUITING

Mesa, Arizona, 85206, United States
Ironwood Cancer & Research Centers
RECRUITING

Phoenix, Arizona, 85028, United States
Ironwood Cancer & Research Centers
RECRUITING

Scottsdale, Arizona, 85260, United States
Jewish General Hospital
RECRUITING

Montreal, Quebec, H3T 1E2, Canada
Kanazawa University Hospital
RECRUITING

Kanazawa, Ishikawa-ken, 920-8641, Japan
Kaohsiung Medical University Chung-Ho Memorial Hospital
RECRUITING

Kaohsiung City, 807, Taiwan
Keio university hospital
RECRUITING

Shinjuku-ku, Tokyo, 1608582, Japan
Kobe University Hospital
RECRUITING

Kobe, Hyōgo, 650-0017, Japan
Kyungpook National University Chilgok Hospital
RECRUITING

Deagu, Taegu-kwangyǒkshi, 41404, South Korea
Lanzhou university second hospital
RECRUITING

Lanzhou, Gansu, 730030, China
MBAL Uni Hospital
NOT_YET_RECRUITING

Panagyurishte, Pazardzhik, 4500, Bulgaria
MILAB, s.r.o., Urologicka ambulancia
RECRUITING

Prešov, 08 001, Slovakia
Maidstone Hospital
NOT_YET_RECRUITING

Maidstone, KENT, ME16 9QQ, United Kingdom
Masarykuv onkologicky ustav
NOT_YET_RECRUITING

Brno, 656 53, Czechia
Mater Misericordiae Limited Mater Cancer Care Centre
RECRUITING

South Brisbane, Queensland, 4101, Australia
Medical Center Futuremeds
RECRUITING

Plovdiv, 4000, Bulgaria
Montefiore Einstein Comprehensive Cancer Center
RECRUITING

The Bronx, New York, 10461, United States
Montefiore Medical Center- Montefiore Medical Park
RECRUITING

The Bronx, New York, 10461, United States
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School
RECRUITING

Nanjing, Jiangsu, 210008, China
Nantong Tumor Hospital
RECRUITING

Nantong, Jiangsu, 226361, China
National Cancer Center
NOT_YET_RECRUITING

Goyang-si, Kyǒnggi-do, 10408, South Korea
National Cheng Kung University Hospital
NOT_YET_RECRUITING

Tainan, 704, Taiwan
National Hospital Organization Hokkaido Cancer Center
RECRUITING

Sapporo, Hokkaido, 003-0804, Japan
National Hospital Organization Kumamoto Medical Center
RECRUITING

Kumamoto, 860-0008, Japan
National Hospital Organization Kyushu Cancer Center
RECRUITING

Fukuoka, 811-1395, Japan
National Hospital Organization Shikoku Cancer Center
RECRUITING

Matsuyama, Ehime, 791-0280, Japan
National Taiwan University Hospital
NOT_YET_RECRUITING

Taipei, 10002, Taiwan
Northwest Medical Specialties, PLLC
RECRUITING

Bonney Lake, Washington, 98391, United States
Northwest Medical Specialties, PLLC
RECRUITING

Federal Way, Washington, 98003, United States
Northwest Medical Specialties, PLLC
RECRUITING

Gig Harbor, Washington, 98332, United States
Northwest Medical Specialties, PLLC
RECRUITING

Puyallup, Washington, 98373, United States
Northwest Medical Specialties, PLLC
RECRUITING

Tacoma, Washington, 98405, United States
Orange Health Service
NOT_YET_RECRUITING

Orange, New South Wales, 2800, Australia
Osaka International Cancer Institute
RECRUITING

Osaka, 541-8567, Japan
Palmerston North Hospital
NOT_YET_RECRUITING

Palmerston North, 4414, New Zealand
Parc de Salut Mar - Hospital del Mar
NOT_YET_RECRUITING

Barcelona, Barcelona [barcelona], 08003, Spain
Parkway Surgery Center
RECRUITING

Myrtle Beach, South Carolina, 29572, United States
Peking University First Hospital
NOT_YET_RECRUITING

Beijing, Beijing Municipality, 100034, China
Privatna urologicka ambulancia, s.r.o.
RECRUITING

Trenčín, 911 01, Slovakia
Prostate Cancer Centre
RECRUITING

Calgary, Alberta, T2V 1P9, Canada
Qilu Hospital of Shandong University
RECRUITING

Jinan, Shandong, 250012, China
Rabin Medical Center
RECRUITING

Petah Tikva, Central District, 4941492, Israel
Rambam Health Care Campus
RECRUITING

Haifa, Northern District, 3109601, Israel
Reinier de Graaf Ziekenhuis, locatie Delft
NOT_YET_RECRUITING

Delft, South Holland, 2625 AD, Netherlands
Ronald Reagan UCLA Medical Center - Drug Information Center
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
Royal Blackburn Hospital
NOT_YET_RECRUITING

Blackburn, Blackburn WITH Darwen, BB2 3HH, United Kingdom
Samsung Medical Center
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 06351, South Korea
Seoul National University Bundang Hospital
RECRUITING

Seongnam, Kyǒnggi-do, 13620, South Korea
Seoul National University Hospital
RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03080, South Korea
Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITING

Seoul, Seoul-teukbyeolsi [seoul], 03722, South Korea
Shaare Zedek Medical Center
RECRUITING

Jerusalem, Jerusalem, 9013102, Israel
Sheba Medical Center
RECRUITING

Ramat Gan, Central District, 5265601, Israel
Sir Charles Gairdner Hospital
RECRUITING

Perth, Western Australia, 6009, Australia
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
RECRUITING

Hangzhou, Zhejiang, 310016, China
Sourasky Medical Center
RECRUITING

Tel Aviv, TELL ABĪB, 6423906, Israel
Suining Central Hospital
RECRUITING

Suining, Sichuan, 629000, China
Sun Yat-sen University Cancer Center
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510555, China
Sydney Adventist Hospital
NOT_YET_RECRUITING

Wahroonga, New South Wales, 2076, Australia
Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie
NOT_YET_RECRUITING

Krakow, Lesser Poland Voivodeship, 31-826, Poland
Taichung Veterans General Hospital
RECRUITING

Taichung, 407, Taiwan
Taipei Veterans General Hospital
NOT_YET_RECRUITING

Taipei, 11217, Taiwan
Tauranga Hospital
RECRUITING

Tauranga, Bay of Plenty, 3112, New Zealand
Tergooi MC
NOT_YET_RECRUITING

Hilversum, North Holland, 1212 VG, Netherlands
The Centers for Advanced Urology, LLP d/b/a Keystone Urology Specialists
RECRUITING

Lancaster, Pennsylvania, 17604, United States
The Christie NHS Foundation Trust
RECRUITING

Manchester, M20 4BX, United Kingdom
The First Affiliated Hospital of Chongqing Medical University
RECRUITING

Chongqing, Chongqing Municipality, 400016, China
The First Affiliated Hospital of Guangzhou Medical University
NOT_YET_RECRUITING

Guangzhou, Guangdong, 510120, China
The First Affiliated Hospital of Wenzhou Medical University
RECRUITING

Wenzhou, Zhejiang, 325000, China
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITING

Xi'an, Shaanxi, 710061, China
The Second Affiliated Hospital of Soochow University
RECRUITING

Suzhou, Jiangsu, 215004, China
The Third Affiliated Hospital of Southern Medical University
RECRUITING

Guangzhou, 510635, China
The University of Osaka Hospital
RECRUITING

Suita, Osaka, 565-0871, Japan
The first affiliated hospital of Ningbo university
RECRUITING

Ningbo, Zhejiang, 315010, China
Torbay Hospital
RECRUITING

Torquay, Devon, TQ2 7AA, United Kingdom
TriState Urologic Services PSC Inc. dba The Urology Group
RECRUITING

Cincinnati, Ohio, 45212, United States
UCLA Department of Medicine - Hematology/Oncology
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
UCLA Hematology/Oncology
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
UCLA Hematology/Oncology - Alhambra
NOT_YET_RECRUITING

Alhambra, California, 91801, United States
UCLA Hematology/Oncology - Atascadero
NOT_YET_RECRUITING

Atascadero, California, 93422, United States
UCLA Hematology/Oncology - Beverly Hills
NOT_YET_RECRUITING

Beverly Hills, California, 90212, United States
UCLA Hematology/Oncology - Burbank
NOT_YET_RECRUITING

Burbank, California, 91505, United States
UCLA Hematology/Oncology - Encino
NOT_YET_RECRUITING

Encino, California, 91436, United States
UCLA Hematology/Oncology - Irvine
NOT_YET_RECRUITING

Irvine, California, 92604, United States
UCLA Hematology/Oncology - Laguna Hills
NOT_YET_RECRUITING

Laguna Hills, California, 92653, United States
UCLA Hematology/Oncology - Marina del Rey
NOT_YET_RECRUITING

Marina del Rey, California, 90292, United States
UCLA Hematology/Oncology - Pasadena
NOT_YET_RECRUITING

Pasadena, California, 91105, United States
UCLA Hematology/Oncology - Porter Ranch
NOT_YET_RECRUITING

Porter Ranch, California, 91326, United States
UCLA Hematology/Oncology - San Luis Obispo
NOT_YET_RECRUITING

San Luis Obispo, California, 93401, United States
UCLA Hematology/Oncology - Santa Barbara
NOT_YET_RECRUITING

Santa Barbara, California, 93101, United States
UCLA Hematology/Oncology - Santa Clarita
NOT_YET_RECRUITING

Valencia, California, 91355, United States
UCLA Hematology/Oncology - Torrance
NOT_YET_RECRUITING

Torrance, California, 90505, United States
UCLA Hematology/Oncology - Ventura
NOT_YET_RECRUITING

Ventura, California, 93003, United States
UCLA Hematology/Oncology - Westlake
NOT_YET_RECRUITING

Westlake Village, California, 91361, United States
UCLA Hematology/Oncology- Santa Monica
NOT_YET_RECRUITING

Santa Monica, California, 90404, United States
UH Minoff Health Center at Chagrin Highlands
RECRUITING

Orange, Ohio, 44122, United States
US Oncology Investigational Product Center (IPC)
RECRUITING

Irving, Texas, 75063, United States
UZ Leuven
RECRUITING

Leuven, Vlaams-brabant, 3000, Belgium
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING

Wuhan, Hubei, 430022, China
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University Hospitals Seidman Cancer Center at UH Avon Health Center
RECRUITING

Avon, Ohio, 44011, United States
University Hospitals Seidman Cancer Center at UH Mentor Health Center
RECRUITING

Mentor, Ohio, 44060, United States
University of Rochester Medical Center
NOT_YET_RECRUITING

Rochester, New York, 14642, United States
University of Rochester, Cancer Center Pharmacy (Investigational Product)
NOT_YET_RECRUITING

Rochester, New York, 14642, United States
University of Texas Southwestern Medical Center - Simmons Cancer Center
NOT_YET_RECRUITING

Dallas, Texas, 75235, United States
University of Texas Southwestern Medical Center - William P. Clements, Jr., University Hospital
NOT_YET_RECRUITING

Dallas, Texas, 75235, United States
University of Texas Southwestern Medical Center-Zale Lipshy University Hospital
NOT_YET_RECRUITING

Dallas, Texas, 75390, United States
University of Texas Southwestern Simmons Cancer Center - Fort Worth
NOT_YET_RECRUITING

Fort Worth, Texas, 76104, United States
University of Texas Southwestern Simmons Cancer Center - Redbird
NOT_YET_RECRUITING

Dallas, Texas, 75237, United States
University of Texas Southwestern Simmons Cancer Center - Richardson/Plano
NOT_YET_RECRUITING

Richardson, Texas, 75080, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
NOT_YET_RECRUITING

Madison, Wisconsin, 53718, United States
University of Wisconsin Carbone Cancer Center - University Hospital
NOT_YET_RECRUITING

Madison, Wisconsin, 53792, United States
UniversitätsSpital Zürich
NOT_YET_RECRUITING

Zurich, 8091, Switzerland
Universitätsklinikum Münster - Albert Schweitzer Campus
NOT_YET_RECRUITING

Münster, North Rhine-Westphalia, 48149, Germany
Urocentrum Praha s.r.o.
RECRUITING

Prague, 120 00, Czechia
Urologie Neandertal - Praxis Mettmann
NOT_YET_RECRUITING

Mettmann, North Rhine-Westphalia, 40822, Germany
Urology Associates, P.C.
RECRUITING

Nashville, Tennessee, 37209, United States
Waikato Hospital
NOT_YET_RECRUITING

Hamilton, Waikato Region, 3204, New Zealand
Wannan Medical College Yijishan Hospital
RECRUITING

Wuhu, Anhui, 241001, China
Yamagata University Hospital
RECRUITING

Yamagata, 990-9585, Japan
Yitzhak Shamir Medical Center
RECRUITING

Ẕerifin, Central District, 70300, Israel
Yokohama City University Medical Center
RECRUITING

Yokohama, Kanagawa, 232-0024, Japan
Yokosuka Kyosai Hospital
RECRUITING

Yokosuka, Kanagawa, 238-8558, Japan
Zachodniopomorskie Centrum Onkologii
NOT_YET_RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-730, Poland
Zhejiang Provincial People's Hospital
NOT_YET_RECRUITING

Hangzhou, Zhejiang, 310014, China

Conditions

Explore the condition pages connected to this study.

CANCER OF THE PROSTATE HORMONE SENSITIVE PROSTATE CANCER METASTATIC CASTRATION SENSITIVE PROSTATE CANCER (MCSPC) PROSTATE CANCER