Scientists test aggressive new combo to beat tough prostate cancer

NCT ID NCT01546987

Completed Disease control Sponsor: Radiation Therapy Oncology Group Source: ClinicalTrials.gov ↗

Summary

This study tested if adding a new hormone-blocking drug (TAK-700) to standard hormone therapy and radiation could better control high-risk prostate cancer. It involved 239 men and compared the new combination against the standard treatment. The main goals were to see if the stronger treatment helped patients live longer and kept the cancer from returning.

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Contacts and locations

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Locations

Adams Cancer Center

Gettysburg, Pennsylvania, 17325, United States
Akron General Medical Center

Akron, Ohio, 44307, United States
Allan Blair Cancer Centre

Regina, Saskatchewan, S4T 7T1, Canada
Appleton Medical Center

Appleton, Wisconsin, 54911, United States
Arizona Oncology Services Foundation

Scottsdale, Arizona, 85260, United States
Arizona Oncology-Deer Valley Center

Phoenix, Arizona, 85027, United States
Atlanta VA Medical Center

Decatur, Georgia, 30033, United States
BCCA-Cancer Centre for the Southern Interior

Kelowna, British Columbia, V1Y 5L3, Canada
Barnes-Jewish West County Hospital

St Louis, Missouri, 63141, United States
Bay Area Medical Center

Marinette, Wisconsin, 54143, United States
Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405, United States
Beth Israel Deaconess Medical Center

Boston, Massachusetts, 02215, United States
Bixby Medical Center

Adrian, Michigan, 49221, United States
Brigham and Women's Hospital

Boston, Massachusetts, 02115, United States
CHUM - Hopital Notre-Dame

Montreal, Quebec, H2L 4M1, Canada
Case Western Reserve University

Cleveland, Ohio, 44106, United States
Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States
Cherry Tree Cancer Center

Hanover, Pennsylvania, 17331, United States
Christiana Care Health System-Christiana Hospital

Newark, Delaware, 19718, United States
Clement J. Zablocki VA Medical Center

Milwaukee, Wisconsin, 53295, United States
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Columbia Saint Mary's Hospital - Ozaukee

Mequon, Wisconsin, 53097, United States
Columbia Saint Mary's Water Tower Medical Commons

Milwaukee, Wisconsin, 53211, United States
Concord Hospital

Concord, New Hampshire, 03301, United States
Cooper Hospital University Medical Center

Camden, New Jersey, 08103, United States
Dana-Farber Cancer Institute

Boston, Massachusetts, 02115, United States
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional

Milford, Massachusetts, 01757, United States
Dana-Farber/Brigham and Women's Cancer Center at South Shore

South Weymouth, Massachusetts, 02190, United States
Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, 03756, United States
Decatur Memorial Hospital

Decatur, Illinois, 62526, United States
Delaware County Memorial Hospital

Drexel Hill, Pennsylvania, 19026, United States
Dixie Medical Center Regional Cancer Center

St. George, Utah, 84770, United States
Door County Cancer Center

Sturgeon Bay, Wisconsin, 54235-1495, United States
Elliot Hospital

Manchester, New Hampshire, 03103, United States
Emory University/Winship Cancer Institute

Atlanta, Georgia, 30322, United States
Exeter Hospital

Exeter, New Hampshire, 03833, United States
Florida Hospital

Orlando, Florida, 32803, United States
Flower Hospital

Sylvania, Ohio, 43560, United States
Fox Chase Cancer Center

Philadelphia, Pennsylvania, 19111, United States
Froedtert and the Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States
Geaugra Hospital

Chardon, Ohio, 44024, United States
Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States
Grady Health System

Atlanta, Georgia, 30303, United States
Great Lakes Cancer Institute-Lapeer Campus

Lapeer, Michigan, 48446, United States
Gundersen Lutheran

La Crosse, Wisconsin, 54601, United States
Hartford Hospital

Hartford, Connecticut, 06102, United States
Helen F Graham Cancer Center

Newark, Delaware, 19713, United States
Hines Veterans Administration Hospital

Hines, Illinois, 60141, United States
Idaho Urologic Institute PA

Meridian, Idaho, 83642, United States
Intermountain Medical Center

Murray, Utah, 84157, United States
Ireland Cancer Center at Firelands Regional Medical Center

Sandusky, Ohio, 44870, United States
Kaiser Permanente Cancer Treatment Center

South San Francisco, California, 94080, United States
Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States
Kansas City Cancer Center - South

Kansas City, Missouri, 64131, United States
Kansas City Cancer Center-Lee's Summit

Lee's Summit, Missouri, 64064, United States
Kansas City Cancer Centers - North

Kansas City, Missouri, 64154, United States
Kansas City Cancer Centers-Southwest

Overland Park, Kansas, 66210, United States
Lake University Ireland Cancer Center

Mentor, Ohio, 44060, United States
Lankenau Hospital

Wynnewood, Pennsylvania, 19096, United States
Lexington Medical Center

West Columbia, South Carolina, 29169, United States
London Regional Cancer Program

London, Ontario, N6A 4L6, Canada
Los Angeles County-USC Medical Center

Los Angeles, California, 90033, United States
Loyola University Medical Center

Maywood, Illinois, 60153, United States
M D Anderson Cancer Center

Houston, Texas, 77030, United States
MD Anderson Cancer Center at Cooper-Voorhees

Voorhees Township, New Jersey, 08043, United States
Maine Medical Center- Scarborough Campus

Scarborough, Maine, 04074, United States
Mary Bird Perkins Cancer Center

Baton Rouge, Louisiana, 70809, United States
Massachusetts General Hospital Cancer Center

Boston, Massachusetts, 02114, United States
McLaren Cancer Institute-Owosso

Owosso, Michigan, 48867, United States
McLaren-Flint

Flint, Michigan, 48532, United States
Memorial Hermann Memorial City Medical Center

Houston, Texas, 77024, United States
Mercy Cancer Center-Elyria

Elyria, Ohio, 44035, United States
Mercy Hospital Springfield

Springfield, Missouri, 65804, United States
Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States
Natalie Warren Bryant Cancer Center at Saint Francis

Tulsa, Oklahoma, 74136, United States
Nebraska Methodist Hospital

Omaha, Nebraska, 68114, United States
North Shore Medical Center Cancer Center

Peabody, Massachusetts, 01960, United States
Northern Michigan Regional Hospital

Petoskey, Michigan, 49770, United States
OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States
Ochsner Medical Center Jefferson

New Orleans, Louisiana, 70121, United States
Ohio State University Medical Center

Columbus, Ohio, 43210, United States
Oncology and Hematology Associates of Southwest Virginia

Roanoke, Virginia, 24014, United States
Ottawa Health Research Institute-General Division

Ottawa, Ontario, K1H 1C4, Canada
Paoli Memorial Hospital

Paoli, Pennsylvania, 19301, United States
Parkview Hospital Randallia

Fort Wayne, Indiana, 46805, United States
Peninsula Regional Medical Center

Salisbury, Maryland, 21801, United States
Piedmont Hospital

Atlanta, Georgia, 30309, United States
Pomona Valley Hospital Medical Center

Pomona, California, 91767, United States
Poudre Valley Radiation Oncology

Fort Collins, Colorado, 80528, United States
Queen's Medical Center

Honolulu, Hawaii, 96813, United States
Radiation Oncology Associates PC

Fort Wayne, Indiana, 46804, United States
Rapid City Regional Hospital

Rapid City, South Dakota, 57701, United States
Reading Hospital

West Reading, Pennsylvania, 19611, United States
Regions Hospital

Saint Paul, Minnesota, 55101, United States
Robinson Radiation Oncology

Ravenna, Ohio, 44266, United States
Rogue Valley Medical Center

Medford, Oregon, 97504, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Saint Agnes Hospital

Baltimore, Maryland, 21229, United States
Saint Alphonsus Regional Medical Center

Boise, Idaho, 83706, United States
Saint Anne's Hospital

Fall River, Massachusetts, 02721, United States
Saint Francis Hospital

Federal Way, Washington, 98003, United States
Saint John's Mercy Medical Center

St Louis, Missouri, 63141, United States
Saint Joseph Mercy Hospital

Ann Arbor, Michigan, 48106-0995, United States
Saint Joseph's-Candler Health System

Savannah, Georgia, 31405, United States
Saint Luke's Hospital of Duluth

Duluth, Minnesota, 55805, United States
Saint Mary's Hospital

Green Bay, Wisconsin, 54303, United States
Saint Peter's University Hospital

New Brunswick, New Jersey, 08901, United States
Saint Vincent Hospital

Green Bay, Wisconsin, 54301, United States
Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States
Sanford Clinic North-Bemidgi

Bemidji, Minnesota, 56601, United States
Sanford Medical Center-Fargo

Fargo, North Dakota, 58122, United States
Saskatoon Cancer Centre

Saskatoon, Saskatchewan, S7N 4H4, Canada
Sentara Cancer Institute at Sentara CarePlex Hospital

Hampton, Virginia, 23666, United States
Sentara Hospitals

Norfolk, Virginia, 23507, United States
Sentara Virginia Beach General Hospital

Virginia Beach, Virginia, 23454, United States
Siteman Cancer Center - Saint Peters

City of Saint Peters, Missouri, 63376, United States
Siteman Cancer Center-South County

St Louis, Missouri, 63129, United States
Southeast Cancer Center

Cape Girardeau, Missouri, 63703, United States
Southwest General Health Center Ireland Cancer Center

Middleburg Heights, Ohio, 44130, United States
Spartanburg Regional Medical Center

Spartanburg, South Carolina, 29303, United States
Stanford University Hospitals and Clinics

Stanford, California, 94305, United States
Summa Akron City Hospital/Cooper Cancer Center

Akron, Ohio, 44304, United States
Summa Barberton Hospital

Barberton, Ohio, 44203, United States
Summa Health Center at Lake Medina

Medina, Ohio, 44256, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn

Auburn, California, 95603, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Cameron Park, California, 95682, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville

Roseville, California, 95661, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville

Vacaville, California, 95687, United States
Sutter General Hospital

Sacramento, California, 95816, United States
Sutter Solano Medical Center

Vallejo, California, 94589, United States
Temple University Hospital

Philadelphia, Pennsylvania, 19140, United States
Texas Cancer Center-Sherman

Sherman, Texas, 75090, United States
Texas Oncology Cancer Center Sugar Land

Sugar Land, Texas, 77479, United States
Texas Oncology PA - Bedford

Bedford, Texas, 76022, United States
The Hospital of Central Connecticut

New Britain, Connecticut, 06050, United States
The Kirklin Clinic at Acton Road

Birmingham, Alabama, 35243, United States
The Klabzuba Cancer Center

Fort Worth, Texas, 76104, United States
The Nebraska Medical Center

Omaha, Nebraska, 68198, United States
The Regional Cancer Center

Erie, Pennsylvania, 16505, United States
Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, 19107, United States
Tom Baker Cancer Centre

Calgary, Alberta, T2N 4N2, Canada
Touro Infirmary

New Orleans, Louisiana, 70115, United States
UCSF-Mount Zion

San Francisco, California, 94115, United States
UHHS-Chagrin Highlands Medical Center

Orange, Ohio, 44122, United States
UHHS-Westlake Medical Center

Westlake, Ohio, 44145, United States
UTMB Cancer Center at Victory Lakes

League City, Texas, 77573, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of California At San Diego

San Diego, California, 92103, United States
University of Cincinnati

Cincinnati, Ohio, 45267, United States
University of Colorado Cancer Center - Anschutz Cancer Pavilion

Aurora, Colorado, 80045, United States
University of Iowa Hospitals and Clinics

Iowa City, Iowa, 52242, United States
University of Kansas Medical Center

Kansas City, Kansas, 66160, United States
University of Kentucky

Lexington, Kentucky, 40536, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center

Miami, Florida, 33136, United States
University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach

Deerfield Beach, Florida, 33442, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Oklahoma Health Sciences Center

Oklahoma City, Oklahoma, 73104, United States
University of Southern California/Norris Cancer Center

Los Angeles, California, 90033, United States
University of Texas Medical Branch at Galveston

Galveston, Texas, 77555-0565, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States
Veterans Administration Long Beach Medical Center

Long Beach, California, 90822, United States
Virginia Mason CCOP

Seattle, Washington, 98101, United States
Washington University School of Medicine

St Louis, Missouri, 63110, United States
Weiss Memorial Hospital

Chicago, Illinois, 60640, United States
WellSpan Health-York Hospital

York, Pennsylvania, 17405, United States
West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States
Wheaton Franciscan Cancer Care - All Saints

Racine, Wisconsin, 53405, United States
William Backus Hospital

Norwich, Connecticut, 06360, United States
William Beaumont Hospital - Troy

Troy, Michigan, 48098, United States
William Beaumont Hospital-Royal Oak

Royal Oak, Michigan, 48073, United States

Conditions

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