New ultrasound could rival MRI for prostate cancer detection

NCT ID NCT06626022

Recruiting now Diagnosis Sponsor: University of Alberta Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial compares a new high-resolution micro-ultrasound to the standard MRI for detecting significant prostate cancer in men aged 50-70 with elevated PSA. About 1,284 participants will be randomly assigned to one imaging method before deciding on biopsy. The goal is to see if the ultrasound is as good as MRI, potentially offering a faster, cheaper screening option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: micro-ultrasound (ExactVu) and MRI
What this could lead to: If successful, micro-ultrasound could become a more accessible and cheaper alternative to MRI for prostate cancer screening, potentially improving early detection rates.
What could go wrong: This is a non-inferiority trial, so micro-ultrasound may prove less effective than MRI. The study is still recruiting, and results are not yet available.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER SCREENING

Contacts and locations

Locations

CH de Martigues
RECRUITING

Martigues, France
CIUSSS du Nord-de-l'Île-de-Montréal
NOT_YET_RECRUITING

Montréal, Quebec, H4J 1C5, Canada
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada
UT Southwestern Medical Center
NOT_YET_RECRUITING

Dallas, Texas, 75390, United States
University of Alberta
ACTIVE_NOT_RECRUITING

Edmonton, Alberta, T6G 1Z1, Canada
University of British Columbia
NOT_YET_RECRUITING

Vancouver, British Columbia, V5Z 1M9, Canada
University of California, Los Angeles (UCLA)
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
Urologia Clinica Bilbao
RECRUITING

Bilbao, Spain
Vestfold Hospital Trust
RECRUITING

Tønsberg, Norway

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