Gene + MRI combo may spot deadly prostate cancer before it spreads

NCT ID NCT06398639

First seen Nov 10, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study is testing a new way to screen for dangerous prostate cancer. It combines a person's genetic risk score with a special MRI to find higher-grade cancers that could be life-threatening. About 1,500 men aged 40-69 with no prior prostate cancer will get a PSA blood test, an MRI, and their genetic risk results. The goal is to see if this approach works better than current methods and to learn at what age MRI screening becomes useful.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02155, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Howard University Hospital

    NOT_YET_RECRUITING

    Washington D.C., District of Columbia, 20060, United States

    Contact

    Contact

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Institute

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Walter Reed National Military Medical Center

    NOT_YET_RECRUITING

    Bethesda, Maryland, 20814, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.