New study tests shorter radiation for tough prostate cancers
NCT ID NCT06235697
First seen Oct 31, 2025 · Last updated May 15, 2026 · Updated 34 times
Summary
This study compares two ways to give high-dose radiation for men with unfavorable-risk prostate cancer that has not spread. One method uses a special machine to deliver radiation in fewer, stronger sessions (SBRT). The other combines standard external radiation with a temporary radioactive implant (brachytherapy boost). The goal is to see if the shorter SBRT approach works as well at controlling the cancer. About 710 men will take part, and all will also receive hormone therapy.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Allegheny General Hospital
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Billings Clinic Cancer Center
RECRUITINGBillings, Montana, 59101, United States
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Bon Secours Cancer Institute at Reynolds Crossing
RECRUITINGRichmond, Virginia, 23230, United States
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Bon Secours Saint Francis Medical Center
RECRUITINGMidlothian, Virginia, 23114, United States
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CHUM - Centre Hospitalier de l'Universite de Montreal
RECRUITINGMontreal, Quebec, H2X 3E4, Canada
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Doctor H. Bliss Murphy Cancer Centre
RECRUITINGSt. John's, Newfoundland and Labrador, A1B 3V6, Canada
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Forbes Hospital
RECRUITINGMonroeville, Pennsylvania, 15146, United States
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Jefferson Hospital
RECRUITINGJefferson Hills, Pennsylvania, 15025, United States
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Jewish General Hospital
RECRUITINGMontreal, Quebec, H3T 1E2, Canada
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Kaiser Permanente Cancer Treatment Center
RECRUITINGSouth San Francisco, California, 94080, United States
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Kaiser Permanente Downtown Commons
RECRUITINGSacramento, California, 95814, United States
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Kaiser Permanente Dublin
RECRUITINGDublin, California, 94568, United States
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Kaiser Permanente Fresno Orchard Plaza
RECRUITINGFresno, California, 93720, United States
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Kaiser Permanente Medical Center - Santa Clara
RECRUITINGSanta Clara, California, 95051, United States
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Kaiser Permanente Medical Center-Vacaville
RECRUITINGVacaville, California, 95688, United States
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Kaiser Permanente Oakland-Broadway
RECRUITINGOakland, California, 94611, United States
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Kaiser Permanente San Leandro
RECRUITINGSan Leandro, California, 94577, United States
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Kaiser Permanente- Marshall Medical Offices
RECRUITINGRedwood City, California, 94063, United States
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Kaiser Permanente-Deer Valley Medical Center
RECRUITINGAntioch, California, 94531, United States
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Kaiser Permanente-Fremont
RECRUITINGFremont, California, 94538, United States
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Kaiser Permanente-Fresno
RECRUITINGFresno, California, 93720, United States
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Kaiser Permanente-Modesto
RECRUITINGModesto, California, 95356, United States
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Kaiser Permanente-Oakland
RECRUITINGOakland, California, 94611, United States
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Kaiser Permanente-Richmond
RECRUITINGRichmond, California, 94801, United States
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Kaiser Permanente-Roseville
RECRUITINGRoseville, California, 95661, United States
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Kaiser Permanente-San Francisco
RECRUITINGSan Francisco, California, 94115, United States
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Kaiser Permanente-Santa Rosa
RECRUITINGSanta Rosa, California, 95403, United States
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Kaiser Permanente-Santa Teresa-San Jose
RECRUITINGSan Jose, California, 95119, United States
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Kaiser Permanente-South Sacramento
RECRUITINGSacramento, California, 95823, United States
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Kaiser Permanente-South San Francisco
RECRUITINGSouth San Francisco, California, 94080, United States
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Kaiser Permanente-Stockton
RECRUITINGStockton, California, 95210, United States
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Kaiser Permanente-Vallejo
RECRUITINGVallejo, California, 94589, United States
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Kaiser Permanente-Walnut Creek
RECRUITINGWalnut Creek, California, 94596, United States
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Kaiser San Rafael-Gallinas
RECRUITINGSan Rafael, California, 94903, United States
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Kingston Health Sciences Centre
RECRUITINGKingston, Ontario, K7L 2V7, Canada
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Lakeridge Health Oshawa
RECRUITINGOshawa, Ontario, L1G 2B9, Canada
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Lenox Hill Hospital
RECRUITINGNew York, New York, 10075, United States
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London Regional Cancer Program
RECRUITINGLondon, Ontario, N6A 4L6, Canada
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Manhattan Eye Ear and Throat Hospital
RECRUITINGNew York, New York, 10065, United States
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Memorial Hospital East
RECRUITINGShiloh, Illinois, 62269, United States
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Northwell Health/Center for Advanced Medicine
RECRUITINGLake Success, New York, 11042, United States
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Odette Cancer Centre- Sunnybrook Health Sciences Centre
RECRUITINGToronto, Ontario, M4N 3M5, Canada
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Rohnert Park Cancer Center
RECRUITINGRohnert Park, California, 94928, United States
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Royal Victoria Regional Health Centre
RECRUITINGBarrie, Ontario, L4M 6M2, Canada
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Saint Vincent Hospital
RECRUITINGErie, Pennsylvania, 16544, United States
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Siteman Cancer Center at Christian Hospital
RECRUITINGSt Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
RECRUITINGCity of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
RECRUITINGCreve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
RECRUITINGSt Louis, Missouri, 63129, United States
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The Permanente Medical Group-Roseville Radiation Oncology
RECRUITINGRoseville, California, 95678, United States
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Trillium Health Partners - Credit Valley Hospital
RECRUITINGMississauga, Ontario, L5M 2N1, Canada
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University Health Network-Princess Margaret Hospital
RECRUITINGToronto, Ontario, M5G 2M9, Canada
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VCU Massey Comprehensive Cancer Center
RECRUITINGRichmond, Virginia, 23298, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63110, United States
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Waterloo Regional Health Network
RECRUITINGKitchener, Ontario, N2G 1G3, Canada
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West Penn Hospital
RECRUITINGPittsburgh, Pennsylvania, 15224, United States
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Wexford Health and Wellness Pavilion
RECRUITINGWexford, Pennsylvania, 15090, United States
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Conditions
Explore the condition pages connected to this study.