Radiation combo vs. single treatment: which works best for prostate cancer?

NCT ID NCT00063882

Completed Disease control Sponsor: Radiation Therapy Oncology Group Source: ClinicalTrials.gov ↗

Summary

This study aimed to find the best radiation treatment for men with intermediate-risk prostate cancer. It compared a two-part treatment (external beam radiation plus internal seed implants) against using the seed implants alone. The goal was to see which approach better controlled the cancer over five years while also comparing side effects and quality of life for nearly 600 participants.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Study site

Santa Clara, California, 95051, United States
Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States
All Saints Cancer Center at Wheaton Franciscan Healthcare

Racine, Wisconsin, 53405, United States
Alta Bates Summit Comprehensive Cancer Center

Berkeley, California, 94704, United States
Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States
Arizona Oncology Services Foundation

Phoenix, Arizona, 85013, United States
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center

Columbus, Ohio, 43210-1240, United States
Auburn Radiation Oncology

Auburn, California, 95603, United States
Barberton Citizens Hospital

Barberton, Ohio, 44203, United States
Barnes-Jewish West County Hospital

St Louis, Missouri, 63141, United States
Bay Area Breast Surgeons, Incorporated

Oakland, California, 94609, United States
Beth Israel Medical Center - Petrie Division

New York, New York, 10003-3803, United States
Blumenthal Cancer Center at Carolinas Medical Center

Charlotte, North Carolina, 28232-2861, United States
CCOP - Bay Area Tumor Institute

Oakland, California, 94609, United States
CCOP - Christiana Care Health Services

Newark, Delaware, 19713, United States
CCOP - Columbus

Columbus, Ohio, 43215, United States
CCOP - Kansas City

Prairie Village, Kansas, 66208, United States
CCOP - Michigan Cancer Research Consortium

Ann Arbor, Michigan, 48106, United States
CCOP - Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States
CCOP - Nevada Cancer Research Foundation

Las Vegas, Nevada, 89106, United States
CCOP - Northwest

Tacoma, Washington, 98405, United States
CCOP - Toledo Community Hospital

Toledo, Ohio, 43617, United States
California Cancer Center - Woodward Park Office

Fresno, California, 93720, United States
California Pacific Medical Center - California Campus

San Francisco, California, 94118, United States
Cancer Care Center, Incorporated

Salem, Ohio, 44460, United States
Cancer Institute at St. John's Hospital

Springfield, Illinois, 62702, United States
Cancer Treatment Center

Wooster, Ohio, 44691, United States
Cape Cod Hospital

Hyannis, Massachusetts, 02601, United States
CarolinaEast Cancer Care

New Bern, North Carolina, 28560, United States
Coastal Carolina Radiation Oncology Center

Wilmington, North Carolina, 28401, United States
Coleman Radiation Oncology Center at Carter General Hospital

Morehead City, North Carolina, 28557, United States
Columbia Saint Mary's Hospital - Ozaukee

Mequon, Wisconsin, 53097, United States
Columbia-Saint Mary's Cancer Care Center

Milwaukee, Wisconsin, 53211, United States
Community Cancer Center

Elyria, Ohio, 44035, United States
Community Hospital of Springfield and Clark County

Springfield, Ohio, 45505, United States
Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States
Cross Cancer Institute at University of Alberta

Edmonton, Alberta, T6G 1Z2, Canada
Dixie Regional Medical Center - East Campus

St. George, Utah, 84770, United States
Doctors Hospital at Ohio Health

Columbus, Ohio, 43228, United States
East Bay Radiation Oncology Center

Castro Valley, California, 94546, United States
El Camino Hospital Cancer Center

Mountain View, California, 94040, United States
Ella Milbank Foshay Cancer Center at Jupiter Medical Center

Jupiter, Florida, 33458, United States
Flower Hospital Cancer Center

Sylvania, Ohio, 43560, United States
Foote Memorial Hospital

Jackson, Michigan, 49201, United States
Fox Chase Cancer Center - Philadelphia

Philadelphia, Pennsylvania, 19111-2497, United States
Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton

Marlton, New Jersey, 08053, United States
Fox Chase Virtua Health Cancer Program at Virtua West Jersey

Voorhees Township, New Jersey, 08043, United States
Franciscan Cancer Center at St. Joseph Medical Center

Tacoma, Washington, 98405-3004, United States
Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center

Wilkes-Barre, Pennsylvania, 18711, United States
Fredericksburg Oncology, Incorporated

Fredericksburg, Virginia, 22401, United States
Geisinger Cancer Institute at Geisinger Health

Danville, Pennsylvania, 17822-0001, United States
Genesis - Good Samaritan Hospital

Zanesville, Ohio, 43701, United States
Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States
Good Samaritan Cancer Center

Puyallup, Washington, 98372, United States
Grady Memorial Hospital

Delaware, Ohio, 43015, United States
Grant Medical Center Cancer Care

Columbus, Ohio, 43215, United States
Greenebaum Cancer Center at University of Maryland Medical Center

Baltimore, Maryland, 21201, United States
Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States
Hematology Oncology Center

Elyria, Ohio, 44035, United States
Hickman Cancer Center at Bixby Medical Center

Adrian, Michigan, 49221, United States
Highland Hospital of Rochester

Rochester, New York, 14620, United States
Hospital of Saint Raphael

New Haven, Connecticut, 06511, United States
Hurley Medical Center

Flint, Michigan, 48503, United States
James P. Wilmot Cancer Center at University of Rochester Medical Center

Rochester, New York, 14642, United States
Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

Murray, Utah, 84157, United States
Kaiser Foundation Hospital - San Rafael

San Rafael, California, 94903, United States
Kaiser Permanente - Division of Research - Oakland

Oakland, California, 94611, United States
Kaiser Permanente Medical Center - Hayward

Hayward, California, 94545, United States
Kaiser Permanente Medical Center - Oakland

Oakland, California, 94611, United States
Kaiser Permanente Medical Center - Rancho Cordova

Rancho Cordova, California, 95670, United States
Kaiser Permanente Medical Center - Redwood City

Redwood City, California, 94063, United States
Kaiser Permanente Medical Center - Richmond

Richmond, California, 94801, United States
Kaiser Permanente Medical Center - Roseville

Roseville, California, 95661, United States
Kaiser Permanente Medical Center - Sacramento

Sacramento, California, 95825, United States
Kaiser Permanente Medical Center - San Francisco Geary Campus

San Francisco, California, 94115, United States
Kaiser Permanente Medical Center - Santa Clara Kiely Campus

Santa Clara, California, 95051, United States
Kaiser Permanente Medical Center - Santa Rosa

Santa Rosa, California, 95403, United States
Kaiser Permanente Medical Center - Santa Teresa

San Jose, California, 95119, United States
Kaiser Permanente Medical Center - South San Francisco

South San Francisco, California, 94080, United States
Kaiser Permanente Medical Center - Walnut Creek

Walnut Creek, California, 94596, United States
Kaiser Permanente Medical Facility - Stockton

Stockton, California, 95210, United States
Kingsbury Center for Cancer Care at Cheshire Medical Center

Keene, New Hampshire, 03431, United States
LDS Hospital

Salt Lake City, Utah, 84143, United States
Larry G Strieff MD Medical Corporation

Oakland, California, 94609, United States
Liberty Hospital

Liberty, Missouri, 64068, United States
Licking Memorial Cancer Care Program at Licking Memorial Hospital

Newark, Ohio, 43055, United States
Lima Memorial Hospital

Lima, Ohio, 45804, United States
Logan Regional Hospital

Logan, Utah, 84321, United States
M. D. Anderson Cancer Center at University of Texas

Houston, Texas, 77030-4009, United States
Mayo Clinic Cancer Center

Rochester, Minnesota, 55905, United States
McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Reading, Pennsylvania, 19612-6052, United States
Medical University of Ohio Cancer Center

Toledo, Ohio, 43614, United States
Menorah Medical Center

Overland Park, Kansas, 66209, United States
Mercy Cancer Center at Mercy San Juan Medical Center

Carmichael, California, 95608, United States
Mercy General Hospital

Sacramento, California, 95819, United States
Mercy Hospital of Tiffin

Tiffin, Ohio, 44883, United States
Mercy Regional Cancer Center at Mercy Hospital

Port Huron, Michigan, 48060, United States
Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital

Fort Lauderdale, Florida, 33308, United States
Mount Carmel Health - West Hospital

Columbus, Ohio, 43222, United States
Mount Carmel St. Ann's Cancer Center

Westerville, Ohio, 43081, United States
MultiCare Regional Cancer Center at Tacoma General Hospital

Tacoma, Washington, 98405, United States
Nevada Cancer Institute

Las Vegas, Nevada, 89135, United States
New York Methodist Hospital

Brooklyn, New York, 11215, United States
Norris Cotton Cancer Center - North

Saint Johnsbury, Vermont, 05819, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, 03756-0002, United States
North Coast Cancer Care, Incorporated

Sandusky, Ohio, 44870, United States
North Kansas City Hospital

Kansas City, Missouri, 64116, United States
Northeast Georgia Medical Center

Gainesville, Georgia, 30501, United States
Northwest Ohio Oncology Center

Maumee, Ohio, 43537-1839, United States
Oakwood Cancer Center at Oakwood Hospital and Medical Center

Dearborn, Michigan, 48123-2500, United States
Parvin Radiation Oncology

Kansas City, Missouri, 64116, United States
Peninsula Medical Center

Burlingame, California, 94010, United States
Princess Margaret Hospital

Toronto, Ontario, M5G 2M9, Canada
Radiation Oncology Center

Alliance, Ohio, 44601, United States
Radiation Oncology Center - Roseville

Roseville, California, 95661, United States
Radiation Oncology Centers - Cameron Park

Cameron Park, California, 95682, United States
Radiological Associates of Sacramento Medical Group, Incorporated

Sacramento, California, 95815, United States
Regional Cancer Center at Memorial Medical Center

Springfield, Illinois, 62781-0001, United States
Renown Institute for Cancer at Renown Regional Medical Center

Reno, Nevada, 89502, United States
Research Medical Center

Kansas City, Missouri, 64132, United States
Riverside Methodist Hospital Cancer Care

Columbus, Ohio, 43214-3998, United States
Rohnert Park Cancer Center

Rohnert Park, California, 94928, United States
Roswell Park Cancer Institute

Buffalo, New York, 14263-0001, United States
Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Boise, Idaho, 83706, United States
Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

Hartford, Connecticut, 06105, United States
Saint Joseph Mercy Cancer Center

Ann Arbor, Michigan, 48106-0995, United States
Saint Joseph Oncology, Incorporated

Saint Joseph, Missouri, 64507, United States
Saint Luke's Cancer Institute at Saint Luke's Hospital

Kansas City, Missouri, 64111, United States
Sandra L. Maxwell Cancer Center

Cedar City, Utah, 84720, United States
Sands Cancer Center

Canandiaqua, New York, 14424, United States
Seton Cancer Institute at Saint Mary's - Saginaw

Saginaw, Michigan, 48601, United States
Shields Radiation Oncology Center - Mansfield

Mansfield, Massachusetts, 02048, United States
Sibley Memorial Hospital

Washington D.C., District of Columbia, 20016, United States
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

St Louis, Missouri, 63110, United States
Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters

City of Saint Peters, Missouri, 63376, United States
Solano Radiation Oncology Center

Vacaville, California, 95687, United States
South Atlantic Radiation Oncology, LLC

Supply, North Carolina, 28462, United States
South Sacramento Cancer Center

Sacramento, California, 95823, United States
South Sacramento Kaiser-Permanente Medical Center

Sacramento, California, 95823, United States
South Suburban Oncology Center

Quincy, Massachusetts, 02169, United States
Sparrow Regional Cancer Center

Lansing, Michigan, 48912-1811, United States
St. Agnes Hospital Cancer Center

Baltimore, Maryland, 21229, United States
St. Anne Mercy Hospital

Toledo, Ohio, 43623, United States
St. Charles Mercy Hospital

Oregon, Ohio, 43616, United States
St. Francis Hospital

Federal Way, Washington, 98003, United States
St. John Macomb Hospital

Warren, Michigan, 48093, United States
St. Joseph Medical Center

Kansas City, Missouri, 64114, United States
St. Joseph Mercy Oakland

Pontiac, Michigan, 48341-2985, United States
St. Mary Mercy Hospital

Livonia, Michigan, 48154, United States
St. Vincent Mercy Medical Center

Toledo, Ohio, 43608, United States
Strecker Cancer Center at Marietta Memorial Hospital

Marietta, Ohio, 45750, United States
Summa Center for Cancer Care at Akron City Hospital

Akron, Ohio, 44309-2090, United States
Sutter Health - Western Division Cancer Research Group

Novato, California, 94945, United States
Sutter Solano Medical Center

Vallejo, California, 94589, United States
Toledo Clinic, Incorporated - Main Clinic

Toledo, Ohio, 43623, United States
Toledo Hospital

Toledo, Ohio, 43606, United States
Tom K Lee, Incorporated

Oakland, California, 94609, United States
UCSF Helen Diller Family Comprehensive Cancer Center

San Francisco, California, 94115, United States
University Radiation Oncology at Parkridge Hospital

Rochester, New York, 14626, United States
Utah Cancer Specialists at UCS Cancer Center

Salt Lake City, Utah, 84106, United States
Utah Valley Regional Medical Center - Provo

Provo, Utah, 84604, United States
Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

Ogden, Utah, 84403, United States
Valley Medical Oncology

Fremont, California, 94538, United States
Valley Medical Oncology Consultants - Castro Valley

Castro Valley, California, 94546, United States
Van Elslander Cancer Center at St. John Hospital and Medical Center

Grosse Pointe Woods, Michigan, 48236, United States
Veterans Affairs Medical Center - Richmond

Richmond, Virginia, 23249, United States
Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

Milwaukee, Wisconsin, 53215, United States
West Allis Memorial Hospital

West Allis, Wisconsin, 53227, United States
Winchester Hospital Radiation Oncology Center

Winchester, Massachusetts, 01890, United States
York Cancer Center at Apple Hill Medical Center

York, Pennsylvania, 17405, United States

Conditions

Explore the condition pages connected to this study.

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