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Which biopsy route catches more aggressive prostate cancers?

NCT ID NCT07710807

Recruiting now Diagnosis Sponsor: Ankara Etlik City Hospital Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial compares two ways of taking prostate tissue samples in men with suspicious MRI findings: through the rectum (transrectal) or through the skin between the scrotum and anus (transperineal). Both methods use MRI images to guide the biopsy needle. The main goal is to see if the transperineal approach is at least as good as the transrectal approach at finding clinically significant prostate cancers, while possibly causing fewer infections. The study involves 280 men aged 50 to 75 with PI-RADS 3-5 lesions on MRI.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cognitive fusion prostate biopsy (transperineal or transrectal approach)
What this could lead to
If one approach proves better at detecting aggressive prostate cancers while causing fewer infections, it could become the preferred standard for men with suspicious MRI findings.
What could go wrong
This is a single-center trial with 280 participants, so results may not apply to all hospitals or patient groups. The study compares two established techniques, so a dramatic breakthrough is unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICALLY SIGNIFICANT PROSTATE CANCER COGNITIVE FUSION PROSTATE CANCER

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ankara Etlik City Hospital

    RECRUITING

    Ankara, Yenimahalle, 06170, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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