Brain surgery drug interaction under the microscope
NCT ID NCT06884657
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how the drug mannitol changes levels of the anesthetic propofol in the blood and urine during brain surgery. Forty adults having either supratentorial tumor surgery or pituitary surgery will be enrolled. Half will receive mannitol, the other half a placebo, and propofol levels will be measured to see if mannitol affects anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
mannitol
What this could lead to
If successful, this could help doctors adjust anesthesia doses more precisely when mannitol is used during brain surgery.
What could go wrong
This is a small, early-phase study with only 40 participants. It measures drug levels, not patient outcomes, so direct benefits are uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Çukurova University
RECRUITINGÇukurova, Adana, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••