Brain surgery drug interaction under the microscope
NCT ID NCT06884657
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how the drug mannitol changes levels of the anesthetic propofol in the blood and urine during brain surgery. Forty adults having either supratentorial tumor surgery or pituitary surgery will be enrolled. Half will receive mannitol, the other half a placebo, and propofol levels will be measured to see if mannitol affects anesthesia.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- mannitol
- What this could lead to
- If successful, this could help doctors adjust anesthesia doses more precisely when mannitol is used during brain surgery.
- What could go wrong
- This is a small, early-phase study with only 40 participants. It measures drug levels, not patient outcomes, so direct benefits are uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Çukurova University
RECRUITINGÇukurova, Adana, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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