Stomach lying may cut breathing support needs in sick infants
NCT ID NCT03976895
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether placing infants under 6 months with moderate to severe bronchiolitis on their stomachs (prone position) while on high-flow oxygen could reduce the need for more intensive breathing support. A total of 452 infants in critical care were randomly assigned to lie on their stomachs or backs. The goal was to see if stomach positioning lowered the rate of needing non-invasive or invasive ventilation within the first three days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- prone position (lying on stomach)
- What this could lead to
- If effective, placing infants on their stomachs during high-flow oxygen therapy could reduce the need for more invasive breathing support.
- What could go wrong
- This is a completed study, but the benefit may depend on how strictly the positioning protocol is followed. Results may not apply to all infants or hospital settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH ANNECY GENEVOIS Unité de surveillance continue pédiatrique
Épagny, 74370, France
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CH CHAMBERY Unité de surveillance continue pédiatrique
Chambéry, 73000, France
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CH CLERMONT FERRAND Service de réanimation néonatal et pédiatrique, CHU Estaing
Clermont-Ferrand, 63003, France
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CH VILLEFRANCHE Service de pédiatrie néonatologie
Gleizé, 69400, France
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CHU GRENOBLE Service de réanimation pédiatrique Hôpital Couple Enfant
La Tronche, 38700, France
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CHU LENVAL NICE Service de réanimation pédiatrique
Nice, 06200, France
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CHU MONTPELLIER Service de réanimation pédiatrique
Montpellier, 34295, France
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CHU Nantes Unité de surveillance continue pédiatrique Hôpital mère-enfant
Nantes, 44093, France
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CHU SAINT-ETIENNE Service de réanimation pédiatrique
Saint-Priest-en-Jarez, 42270, France
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CHU de Caen, Service de réanimation et surveillance continue pédiatrique
Caen, 14000, France
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CRHU Nancy Réanimation Pédiatrique Spécialisée
Vandœuvre-lès-Nancy, 54500, France
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Hôpital Clocheville Service de réanimation pédiatrique et d'USC médico-chirurgicale CHRU Tours
Tours, 37044, France
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Hôpital Hautepierre CHU de Strasbourg Service de réanimation pédiatrique spécialisée
Strasbourg, 67098, France
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Hôpital Necker Enfant Malade, Paris Service de Réanimation et surveillance continue médicochirurgicales
Paris, 75015, France
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Hôpital d'Enfants CHU de Dijon Service de réanimation pédiatrique
Dijon, 21079, France
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Réanimation pédiatrique et unité de surveillance continue - Hôpital Femme Mère Enfant - Hospices Civils de Lyon
Bron, 69500, France
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