New sealant could cut chest tube time for lung cancer patients

NCT ID NCT07479277

Recruiting now Disease control Sponsor: Fondazione del Piemonte per l'Oncologia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether applying a surgical sealant (Progel Platinum) to staple lines during lung cancer surgery can reduce the time patients need a chest tube. About 160 adults having minimally invasive lung lobectomy for non-small cell lung cancer will be randomly assigned to get the sealant plus staples or staples alone. The main goal is to see if the sealant shortens chest tube duration and hospital stay.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Progel Platinum surgical sealant
What this could lead to: If it works, this could mean fewer days with a chest tube and a shorter hospital stay after lung cancer surgery.
What could go wrong: This is a relatively small, early-stage trial. The sealant may not significantly reduce drainage time, and there is a risk of allergic reaction or other complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER NSCLC POSTOPERATIVE AIR LEAK

Contacts and locations

Locations

Azienda Ospedaliera-Universitaria Pisana
NOT_YET_RECRUITING

Pisa, Italy
Azienda Ospedaliero-Universitaria Careggi
NOT_YET_RECRUITING

Florence, Italy
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
NOT_YET_RECRUITING

Milan, Italy
Irccs Ismett
NOT_YET_RECRUITING

Palermo, Italy
Ospedale centrale di Bolzano, Chirurgia Toracica e Vascolare
NOT_YET_RECRUITING

Bolzano, Italy
Unità di Chirurgia Toracica Oncologica
RECRUITING

Candiolo, Torino, 10060, Italy

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