New donor cartilage implant aims to fix knee damage in one surgery

NCT ID NCT03873545

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a special donor tissue called ProChondrix CR to repair damaged knee cartilage in 34 adults aged 18 to 60. The tissue is implanted during surgery to help reduce pain and improve knee function over 5 years. Researchers will track changes in pain, movement, and quality of life to see if this single-step approach works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ProChondrix CR (cryopreserved donor cartilage and bone tissue)

What this could lead to

If it works, this could provide a single-step surgical option to repair knee cartilage damage, reducing pain and improving mobility without needing multiple procedures.

What could go wrong

This is a small, early-stage study with only 34 participants, so results may not apply to everyone. The implant may fail to integrate or symptoms may not improve significantly.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beacon Orthopaedics & Sports Medicine

    Cincinnati, Ohio, 45247, United States

  • Midwest Orthopaedics at Rush

    Chicago, Illinois, 60612, United States

  • University of Kentucky Research Foundation

    Lexington, Kentucky, 40506, United States