Could a daily probiotic dissolve kidney stone risk?
NCT ID NCT06477471
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial is testing whether an oral probiotic supplement, MetProrenes, can safely reduce the risk of kidney stones in adults who have had recurrent stone-related colicky pain. About 14 participants will take the supplement twice a day, and researchers will measure changes in pain levels and urine markers linked to stone formation, such as calcium, oxalate, and pH. The study also tracks safety through blood tests. It's an early, proof-of-science investigation, so the results will show whether this approach is worth pursuing in larger studies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an oral probiotic supplement called MetProrenes, taken as a slow-release capsule twice daily
- What this could lead to
- If it works, this could point toward a simple, daily probiotic approach to help prevent kidney stones and reduce the pain of stone-related colic.
- What could go wrong
- This is a very small, early-stage study with only 14 participants, so results may not apply broadly. The probiotic's effects on stone risk and pain are uncertain, and it may not prove effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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NovoBliss Research Pvt.Ltd
Ahmedabad, Gujarat, 382481, India