Could a probiotic calm gut inflammation in overweight people?

NCT ID NCT07253155

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a probiotic called Streptococcus thermophilus (FX856) in 100 overweight or obese adults. The goal is to see if it can reduce mild gut inflammation and improve digestive symptoms. Participants will take the probiotic or a placebo in a crossover design, and researchers will measure inflammation markers and symptom scores.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Streptococcus thermophilus (FX856) probiotic
What this could lead to
If it works, this could point toward a simple probiotic supplement to reduce gut inflammation and improve digestive symptoms in people with overweight or obesity.
What could go wrong
This is a small early-stage trial with only 100 people, so results may not apply to everyone. The probiotic may not reduce inflammation or symptoms as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ulster University, Human Intervention Studies Unit

    Coleraine, BT52 1SA, United Kingdom

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Other studies related to the condition(s) this trial covers.